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Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation.
Van Rompay KKA, Olstad KJ, Sammak RL, Dutra J, Watanabe JK, Usachenko JL, Immareddy R, Roh JW, Verma A, Shaan Lakshmanappa Y, Schmidt BA, Di Germanio C, Rizvi N, Liu H, Ma ZM, Stone M, Simmons G, Dumont LJ, Allen AM, Lockwood S, Pollard RE, Ramiro de Assis R, Yee JL, Nham PB, Ardeshir A, Deere JD, Jain A, Felgner PL, Coffey LL, Iyer SS, Hartigan-O'Connor DJ, Busch MP, Reader JR. Van Rompay KKA, et al. Among authors: nham pb. PLoS Pathog. 2022 Apr 20;18(4):e1009925. doi: 10.1371/journal.ppat.1009925. eCollection 2022 Apr. PLoS Pathog. 2022. PMID: 35443018 Free PMC article.
SARS-CoV-2 surveillance for a non-human primate breeding research facility.
Yee JL, Van Rompay KKA, Carpenter AB, Nham PB, Halley BM, Iyer SS, Hartigan-O'Connor DJ, Miller CJ, Roberts JA. Yee JL, et al. Among authors: nham pb. J Med Primatol. 2020 Dec;49(6):322-331. doi: 10.1111/jmp.12483. Epub 2020 Jul 3. J Med Primatol. 2020. PMID: 32621339 Free PMC article.
Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques.
Van Rompay KKA, Olstad KJ, Sammak RL, Dutra J, Watanabe JK, Usachenko JL, Immareddy R, Verma A, Shaan Lakshmanappa Y, Schmidt BA, Roh JW, Elizaldi SR, Allen AM, Muecksch F, Lorenzi JCC, Lockwood S, Pollard RE, Yee JL, Nham PB, Ardeshir A, Deere JD, Patterson J, Dang Q, Hatziioannou T, Bieniasz PD, Iyer SS, Hartigan-O'Connor DJ, Nussenzweig MC, Reader JR. Van Rompay KKA, et al. Among authors: nham pb. PLoS Pathog. 2021 Jul 6;17(7):e1009688. doi: 10.1371/journal.ppat.1009688. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34228761 Free PMC article.
Sylvatic Transmission of Chikungunya Virus among Nonhuman Primates in Myanmar.
Evans TS, Aung O, Cords O, Coffey LL, Wong T, Weiss CM, Maw MT, Yee J, Venkateswaran K, Venkateswaran N, Nham P, Van Rompay KKA, Morris MK, Oceguera L, Werthimer W, Hanson C, Valitutto M, Tun KYN, Win YT, Thein WZ, Murray S, Thu HM, Johnson CK. Evans TS, et al. Emerg Infect Dis. 2022 Dec;28(12):2548-2551. doi: 10.3201/eid2812.220893. Emerg Infect Dis. 2022. PMID: 36417997 Free PMC article.
Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation.
Van Rompay KKA, Olstad KJ, Sammak RL, Dutra J, Watanabe JK, Usachenko JL, Immareddy R, Roh JW, Verma A, Shaan Lakshmanappa Y, Schmidt BA, Di Germanio C, Rizvi N, Stone M, Simmons G, Dumont LJ, Allen AM, Lockwood S, Pollard RE, de Assis RR, Yee JL, Nham PB, Ardeshir A, Deere JD, Patterson J, Jain A, Felgner PL, Iyer SS, Hartigan-O'Connor DJ, Busch MP, Reader JR. Van Rompay KKA, et al. Among authors: nham pb. bioRxiv [Preprint]. 2021 Sep 1:2021.09.01.458520. doi: 10.1101/2021.09.01.458520. bioRxiv. 2021. PMID: 34494025 Free PMC article. Updated. Preprint.
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