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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, Tumwebaze PK, Yeo T, Aguiar ACC, Angulo-Barturen I, Churchyard A, Baum J, Fernández BC, Fuchs A, Gamo FJ, Guido RVC, Jiménez-Diaz MB, Pereira DB, Rochford R, Roesch C, Sanz LM, Trevitt G, Witkowski B, Wittlin S, Cooper RA, Rosenthal PJ, Sauerwein RW, Schalkwijk J, Hermkens PHH, Bonnert RV, Campo B, Fidock DA, Llinás M, Niles JC, Kooij TWA, Dechering KJ. de Vries LE, et al. Among authors: jansen pam. Nat Commun. 2022 Apr 20;13(1):2158. doi: 10.1038/s41467-022-29688-5. Nat Commun. 2022. PMID: 35444200 Free PMC article.
Rho kinase inhibitor Y-27632 prolongs the life span of adult human keratinocytes, enhances skin equivalent development, and facilitates lentiviral transduction.
van den Bogaard EH, Rodijk-Olthuis D, Jansen PA, van Vlijmen-Willems IM, van Erp PE, Joosten I, Zeeuwen PL, Schalkwijk J. van den Bogaard EH, et al. Tissue Eng Part A. 2012 Sep;18(17-18):1827-36. doi: 10.1089/ten.TEA.2011.0616. Epub 2012 Jun 5. Tissue Eng Part A. 2012. PMID: 22519508 Free PMC article.
Novel pantothenate derivatives for anti-malarial chemotherapy.
Pett HE, Jansen PA, Hermkens PH, Botman PN, Beuckens-Schortinghuis CA, Blaauw RH, Graumans W, van de Vegte-Bolmer M, Koolen KM, Rutjes FP, Dechering KJ, Sauerwein RW, Schalkwijk J. Pett HE, et al. Malar J. 2015 Apr 18;14:169. doi: 10.1186/s12936-015-0673-8. Malar J. 2015. PMID: 25927675 Free PMC article.
An In vitro Model for Bacterial Growth on Human Stratum Corneum.
van der Krieken DA, Ederveen TH, van Hijum SA, Jansen PA, Melchers WJ, Scheepers PT, Schalkwijk J, Zeeuwen PL. van der Krieken DA, et al. Acta Derm Venereol. 2016 Nov 2;96(7):873-879. doi: 10.2340/00015555-2401. Acta Derm Venereol. 2016. PMID: 26976779 Free article.
32 results