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SARS-CoV-2 Spike Protein Binding of Glycated Serum Albumin-Its Potential Role in the Pathogenesis of the COVID-19 Clinical Syndromes and Bias towards Individuals with Pre-Diabetes/Type 2 Diabetes and Metabolic Diseases.
Iles J, Zmuidinaite R, Sadee C, Gardiner A, Lacey J, Harding S, Ule J, Roblett D, Heeney J, Baxendale H, Iles RK. Iles J, et al. Among authors: baxendale h. Int J Mol Sci. 2022 Apr 8;23(8):4126. doi: 10.3390/ijms23084126. Int J Mol Sci. 2022. PMID: 35456942 Free PMC article.
Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes.
Whitworth J, Smith PS, Martin JE, West H, Luchetti A, Rodger F, Clark G, Carss K, Stephens J, Stirrups K, Penkett C, Mapeta R, Ashford S, Megy K, Shakeel H, Ahmed M, Adlard J, Barwell J, Brewer C, Casey RT, Armstrong R, Cole T, Evans DG, Fostira F, Greenhalgh L, Hanson H, Henderson A, Hoffman J, Izatt L, Kumar A, Kwong A, Lalloo F, Ong KR, Paterson J, Park SM, Chen-Shtoyerman R, Searle C, Side L, Skytte AB, Snape K, Woodward ER; NIHR BioResource Rare Diseases Consortium; Tischkowitz MD, Maher ER. Whitworth J, et al. Am J Hum Genet. 2018 Jul 5;103(1):3-18. doi: 10.1016/j.ajhg.2018.04.013. Epub 2018 Jun 14. Am J Hum Genet. 2018. PMID: 29909963 Free PMC article.
Autosomal Dominant STAT6 Gain of Function Causes Severe Atopy Associated with Lymphoma.
Minskaia E, Maimaris J, Jenkins P, Albuquerque AS, Hong Y, Eleftheriou D, Gilmour KC, Grace R, Moreira F, Grimbacher B; NIHR Bioresource-Rare Diseases Consortium; Morris EC, Burns SO. Minskaia E, et al. J Clin Immunol. 2023 Oct;43(7):1611-1622. doi: 10.1007/s10875-023-01530-7. Epub 2023 Jun 14. J Clin Immunol. 2023. PMID: 37316763 Free PMC article.
The efficacy and safety of systemic corticosteroids as first line treatment for granulomatous lymphocytic interstitial lung disease.
Smits B, Goldacker S, Seneviratne S, Malphettes M, Longhurst H, Mohamed OE, Witt-Rautenberg C, Leeman L, Schwaneck E, Raymond I, Meghit K, Uhlmann A, Winterhalter C, van Montfrans J, Klima M, Workman S, Fieschi C, Lorenzo L, Boyle S, Onyango-Odera S, Price S, Schmalzing M, Aurillac V, Prasse A, Hartmann I, Meerburg JJ, Kemner-van de Corput M, Tiddens H, Grimbacher B, Kelleher P, Patel SY, Korganow AS, Viallard JF, Tony HP, Bethune C, Schulze-Koops H, Witte T, Huissoon A, Baxendale H, Grigoriadou S, Oksenhendler E, Burns SO, Warnatz K. Smits B, et al. Among authors: baxendale h. J Allergy Clin Immunol. 2023 Aug;152(2):528-537. doi: 10.1016/j.jaci.2022.12.813. Epub 2022 Dec 29. J Allergy Clin Immunol. 2023. PMID: 36587851 Clinical Trial.
A thermostable, closed SARS-CoV-2 spike protein trimer.
Xiong X, Qu K, Ciazynska KA, Hosmillo M, Carter AP, Ebrahimi S, Ke Z, Scheres SHW, Bergamaschi L, Grice GL, Zhang Y; CITIID-NIHR COVID-19 BioResource Collaboration; Nathan JA, Baker S, James LC, Baxendale HE, Goodfellow I, Doffinger R, Briggs JAG. Xiong X, et al. Among authors: baxendale he. Nat Struct Mol Biol. 2020 Oct;27(10):934-941. doi: 10.1038/s41594-020-0478-5. Epub 2020 Jul 31. Nat Struct Mol Biol. 2020. PMID: 32737467 Free PMC article.
Paucity and discordance of neutralising antibody responses to SARS-CoV-2 VOCs in vaccinated immunodeficient patients and health-care workers in the UK.
Nadesalingam A, Cantoni D, Wells DA, Aguinam ET, Ferrari M, Smith P, Chan A, Carnell G, Ohlendorf L, Einhauser S, George C, Wagner R, Temperton N, Castillo-Olivares J, Baxendale H, Heeney JL; HICC consortium. Nadesalingam A, et al. Among authors: baxendale h. Lancet Microbe. 2021 Sep;2(9):e416-e418. doi: 10.1016/S2666-5247(21)00157-9. Epub 2021 Jun 28. Lancet Microbe. 2021. PMID: 34223399 Free PMC article. No abstract available.
Critical Care Workers Have Lower Seroprevalence of SARS-CoV-2 IgG Compared with Non-patient Facing Staff in First Wave of COVID19.
Baxendale HE, Wells D, Gronlund J, Nadesalingham A, Paloniemi M, Carnell G, Tonks P, Ceron-Gutierrez L, Ebrahimi S, Sayer A, Briggs JAG, Ziong X, Nathan JA, Grice G, James LC, Luptak J, Pai S, Heeney JL, Lear S, Doffinger R. Baxendale HE, et al. J Crit Care Med (Targu Mures). 2021 Aug 5;7(3):199-210. doi: 10.2478/jccm-2021-0018. eCollection 2021 Jul. J Crit Care Med (Targu Mures). 2021. PMID: 34722923 Free PMC article.
Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases.
Castillo-Olivares J, Wells DA, Ferrari M, Chan ACY, Smith P, Nadesalingam A, Paloniemi M, Carnell GW, Ohlendorf L, Cantoni D, Mayora-Neto M, Palmer P, Tonks P, Temperton NJ, Peterhoff D, Neckermann P, Wagner R, Doffinger R, Kempster S, Otter AD, Semper A, Brooks T, Albecka A, James LC, Page M, Schwaeble W, Baxendale H, Heeney JL. Castillo-Olivares J, et al. Among authors: baxendale h. Front Immunol. 2021 Nov 19;12:748291. doi: 10.3389/fimmu.2021.748291. eCollection 2021. Front Immunol. 2021. PMID: 34867975 Free PMC article.
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