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JAK inhibitors and COVID-19.
Levy G, Guglielmelli P, Langmuir P, Constantinescu SN. Levy G, et al. Among authors: constantinescu sn. J Immunother Cancer. 2022 Apr;10(4):e002838. doi: 10.1136/jitc-2021-002838. J Immunother Cancer. 2022. PMID: 35459733 Free PMC article. Review.
Mining for JAK-STAT mutations in cancer.
Constantinescu SN, Girardot M, Pecquet C. Constantinescu SN, et al. Trends Biochem Sci. 2008 Mar;33(3):122-31. doi: 10.1016/j.tibs.2007.12.002. Trends Biochem Sci. 2008. PMID: 18291658 Review.
Cooperating JAK1 and JAK3 mutants increase resistance to JAK inhibitors.
Springuel L, Hornakova T, Losdyck E, Lambert F, Leroy E, Constantinescu SN, Flex E, Tartaglia M, Knoops L, Renauld JC. Springuel L, et al. Among authors: constantinescu sn. Blood. 2014 Dec 18;124(26):3924-31. doi: 10.1182/blood-2014-05-576652. Epub 2014 Oct 28. Blood. 2014. PMID: 25352124 Free article.
Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.
Losdyck E, Hornakova T, Springuel L, Degryse S, Gielen O, Cools J, Constantinescu SN, Flex E, Tartaglia M, Renauld JC, Knoops L. Losdyck E, et al. Among authors: constantinescu sn. J Biol Chem. 2015 Nov 27;290(48):29022-34. doi: 10.1074/jbc.M115.670224. Epub 2015 Oct 7. J Biol Chem. 2015. PMID: 26446793 Free PMC article.
216 results