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Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function.
Meisgen S, Hedlund M, Ambrosi A, Folkersen L, Ottosson V, Forsberg D, Thorlacius GE, Biavati L, Strandberg L, Mofors J, Ramskold D, Ruhrmann S, Meneghel L, Nyberg W, Espinosa A, Hamilton RM, Franco-Cereceda A, Hamsten A, Olsson T, Greene L, Eriksson P, Gemzell-Danielsson K, Salomonsson S, Kuchroo VK, Herlenius E, Kockum I, Sonesson SE, Wahren-Herlenius M. Meisgen S, et al. Ann Rheum Dis. 2022 Aug;81(8):1151-1161. doi: 10.1136/annrheumdis-2021-221714. Epub 2022 Apr 25. Ann Rheum Dis. 2022. PMID: 35470161 Free PMC article.
European families reveal MHC class I and II associations with autoimmune-mediated congenital heart block.
Kyriakidis NC, Kockum I, Julkunen H, Hoxha A, Salomonsson S, Meneghel L, Ebbing C; Swedish Congenital Heart Block Study Group; Dilthey A, Eronen M, De Carolis S, Kiserud T, Ruffatti A, Kere J, Meisgen S, Wahren-Herlenius M. Kyriakidis NC, et al. Among authors: meisgen s. Ann Rheum Dis. 2018 Sep;77(9):1381-1382. doi: 10.1136/annrheumdis-2018-212953. Epub 2018 Feb 16. Ann Rheum Dis. 2018. PMID: 29453219 No abstract available.
H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production.
Brauner S, Folkersen L, Kvarnström M, Meisgen S, Petersen S, Franzén-Malmros M, Mofors J, Brokstad KA, Klareskog L, Jonsson R, Westerberg LS, Trollmo C, Malmström V, Ambrosi A, Kuchroo VK, Nordmark G, Wahren-Herlenius M. Brauner S, et al. Among authors: meisgen s. Ann Rheum Dis. 2017 Oct;76(10):1755-1763. doi: 10.1136/annrheumdis-2016-210509. Epub 2017 Jul 31. Ann Rheum Dis. 2017. PMID: 28760805 Free PMC article.
The HLA locus contains novel foetal susceptibility alleles for congenital heart block with significant paternal influence.
Meisgen S, Östberg T, Salomonsson S, Ding B, Eliasson H, Mälarstig A, Alfredsson L, Klareskog L, Hamsten A, Olsson T, Axelsson T; Swedish Congenital Heart Block Study Group; Gadler F, Jonzon A, Sonesson SE, Kockum I, Wahren-Herlenius M. Meisgen S, et al. J Intern Med. 2014 Jun;275(6):640-51. doi: 10.1111/joim.12179. Epub 2014 Jan 20. J Intern Med. 2014. PMID: 24354957 Free article.