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An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern.
Du W, Hurdiss DL, Drabek D, Mykytyn AZ, Kaiser FK, González-Hernández M, Muñoz-Santos D, Lamers MM, van Haperen R, Li W, Drulyte I, Wang C, Sola I, Armando F, Beythien G, Ciurkiewicz M, Baumgärtner W, Guilfoyle K, Smits T, van der Lee J, van Kuppeveld FJM, van Amerongen G, Haagmans BL, Enjuanes L, Osterhaus ADME, Grosveld F, Bosch BJ. Du W, et al. Among authors: van haperen r. Sci Immunol. 2022 Jul 29;7(73):eabp9312. doi: 10.1126/sciimmunol.abp9312. Epub 2022 Jul 29. Sci Immunol. 2022. PMID: 35471062 Free PMC article.
Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein.
Widjaja I, Wang C, van Haperen R, Gutiérrez-Álvarez J, van Dieren B, Okba NMA, Raj VS, Li W, Fernandez-Delgado R, Grosveld F, van Kuppeveld FJM, Haagmans BL, Enjuanes L, Drabek D, Bosch BJ. Widjaja I, et al. Among authors: van haperen r, van dieren b, van kuppeveld fjm. Emerg Microbes Infect. 2019;8(1):516-530. doi: 10.1080/22221751.2019.1597644. Emerg Microbes Infect. 2019. PMID: 30938227 Free PMC article.
A human monoclonal antibody blocking SARS-CoV-2 infection.
Wang C, Li W, Drabek D, Okba NMA, van Haperen R, Osterhaus ADME, van Kuppeveld FJM, Haagmans BL, Grosveld F, Bosch BJ. Wang C, et al. Among authors: van haperen r. Nat Commun. 2020 May 4;11(1):2251. doi: 10.1038/s41467-020-16256-y. Nat Commun. 2020. PMID: 32366817 Free PMC article.
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies.
Wang C, van Haperen R, Gutiérrez-Álvarez J, Li W, Okba NMA, Albulescu I, Widjaja I, van Dieren B, Fernandez-Delgado R, Sola I, Hurdiss DL, Daramola O, Grosveld F, van Kuppeveld FJM, Haagmans BL, Enjuanes L, Drabek D, Bosch BJ. Wang C, et al. Among authors: van haperen r. Nat Commun. 2021 Mar 17;12(1):1715. doi: 10.1038/s41467-021-21968-w. Nat Commun. 2021. PMID: 33731724 Free PMC article.
64 results