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A multi-organ chip with matured tissue niches linked by vascular flow.
Ronaldson-Bouchard K, Teles D, Yeager K, Tavakol DN, Zhao Y, Chramiec A, Tagore S, Summers M, Stylianos S, Tamargo M, Lee BM, Halligan SP, Abaci EH, Guo Z, Jacków J, Pappalardo A, Shih J, Soni RK, Sonar S, German C, Christiano AM, Califano A, Hirschi KK, Chen CS, Przekwas A, Vunjak-Novakovic G. Ronaldson-Bouchard K, et al. Among authors: chen cs. Nat Biomed Eng. 2022 Apr;6(4):351-371. doi: 10.1038/s41551-022-00882-6. Epub 2022 Apr 27. Nat Biomed Eng. 2022. PMID: 35478225 Free PMC article.
Making bone via nanoscale kicks.
Eyckmans J, Chen CS. Eyckmans J, et al. Among authors: chen cs. Nat Biomed Eng. 2017 Sep;1(9):689-690. doi: 10.1038/s41551-017-0133-6. Nat Biomed Eng. 2017. PMID: 31015669 No abstract available.
Stem cell differentiation: sticky mechanical memory.
Eyckmans J, Chen CS. Eyckmans J, et al. Among authors: chen cs. Nat Mater. 2014 Jun;13(6):542-3. doi: 10.1038/nmat3989. Nat Mater. 2014. PMID: 24845990 No abstract available.
A DNA-based molecular probe for optically reporting cellular traction forces.
Blakely BL, Dumelin CE, Trappmann B, McGregor LM, Choi CK, Anthony PC, Duesterberg VK, Baker BM, Block SM, Liu DR, Chen CS. Blakely BL, et al. Among authors: chen cs. Nat Methods. 2014 Dec;11(12):1229-32. doi: 10.1038/nmeth.3145. Epub 2014 Oct 12. Nat Methods. 2014. PMID: 25306545 Free PMC article.
A Bile Duct-on-a-Chip With Organ-Level Functions.
Du Y, Khandekar G, Llewellyn J, Polacheck W, Chen CS, Wells RG. Du Y, et al. Among authors: chen cs. Hepatology. 2020 Apr;71(4):1350-1363. doi: 10.1002/hep.30918. Epub 2019 Oct 28. Hepatology. 2020. PMID: 31465556 Free PMC article.
Mechanical regulation of glycolysis via cytoskeleton architecture.
Park JS, Burckhardt CJ, Lazcano R, Solis LM, Isogai T, Li L, Chen CS, Gao B, Minna JD, Bachoo R, DeBerardinis RJ, Danuser G. Park JS, et al. Among authors: chen cs. Nature. 2020 Feb;578(7796):621-626. doi: 10.1038/s41586-020-1998-1. Epub 2020 Feb 12. Nature. 2020. PMID: 32051585 Free PMC article.
2,375 results