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A multi-organ chip with matured tissue niches linked by vascular flow.
Ronaldson-Bouchard K, Teles D, Yeager K, Tavakol DN, Zhao Y, Chramiec A, Tagore S, Summers M, Stylianos S, Tamargo M, Lee BM, Halligan SP, Abaci EH, Guo Z, Jacków J, Pappalardo A, Shih J, Soni RK, Sonar S, German C, Christiano AM, Califano A, Hirschi KK, Chen CS, Przekwas A, Vunjak-Novakovic G. Ronaldson-Bouchard K, et al. Among authors: hirschi kk. Nat Biomed Eng. 2022 Apr;6(4):351-371. doi: 10.1038/s41551-022-00882-6. Epub 2022 Apr 27. Nat Biomed Eng. 2022. PMID: 35478225 Free PMC article.
Endothelial cell cycle state determines propensity for arterial-venous fate.
Chavkin NW, Genet G, Poulet M, Jeffery ED, Marziano C, Genet N, Vasavada H, Nelson EA, Acharya BR, Kour A, Aragon J, McDonnell SP, Huba M, Sheynkman GM, Walsh K, Hirschi KK. Chavkin NW, et al. Among authors: hirschi kk. Nat Commun. 2022 Oct 6;13(1):5891. doi: 10.1038/s41467-022-33324-7. Nat Commun. 2022. PMID: 36202789 Free PMC article.
FGF-dependent metabolic control of vascular development.
Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M. Yu P, et al. Among authors: hirschi kk. Nature. 2017 May 11;545(7653):224-228. doi: 10.1038/nature22322. Epub 2017 May 3. Nature. 2017. PMID: 28467822 Free PMC article.
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.
Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi MM, Bender JR, Morrison AR. Ceneri N, et al. Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):328-340. doi: 10.1161/ATVBAHA.116.308507. Epub 2016 Nov 10. Arterioscler Thromb Vasc Biol. 2017. PMID: 27834690 Free PMC article.
The molecular basis of endothelial cell plasticity.
Dejana E, Hirschi KK, Simons M. Dejana E, et al. Among authors: hirschi kk. Nat Commun. 2017 Feb 9;8:14361. doi: 10.1038/ncomms14361. Nat Commun. 2017. PMID: 28181491 Free PMC article. Review.
133 results