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Patient-derived micro-organospheres enable clinical precision oncology.
Ding S, Hsu C, Wang Z, Natesh NR, Millen R, Negrete M, Giroux N, Rivera GO, Dohlman A, Bose S, Rotstein T, Spiller K, Yeung A, Sun Z, Jiang C, Xi R, Wilkin B, Randon PM, Williamson I, Nelson DA, Delubac D, Oh S, Rupprecht G, Isaacs J, Jia J, Chen C, Shen JP, Kopetz S, McCall S, Smith A, Gjorevski N, Walz AC, Antonia S, Marrer-Berger E, Clevers H, Hsu D, Shen X. Ding S, et al. Among authors: shen x, shen jp. Cell Stem Cell. 2022 Jun 2;29(6):905-917.e6. doi: 10.1016/j.stem.2022.04.006. Epub 2022 May 3. Cell Stem Cell. 2022. PMID: 35508177 Free PMC article.
Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.
Bu P, Chen KY, Xiang K, Johnson C, Crown SB, Rakhilin N, Ai Y, Wang L, Xi R, Astapova I, Han Y, Li J, Barth BB, Lu M, Gao Z, Mines R, Zhang L, Herman M, Hsu D, Zhang GF, Shen X. Bu P, et al. Among authors: shen x. Cell Metab. 2018 Jun 5;27(6):1249-1262.e4. doi: 10.1016/j.cmet.2018.04.003. Epub 2018 Apr 26. Cell Metab. 2018. PMID: 29706565 Free PMC article.
An imprecise path to precision medicine.
Shen X. Shen X. Nat Med. 2020 Jan;26(1):14. doi: 10.1038/s41591-019-0718-6. Nat Med. 2020. PMID: 31932784 No abstract available.
A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer.
Somarelli JA, Roghani RS, Moghaddam AS, Thomas BC, Rupprecht G, Ware KE, Altunel E, Mantyh JB, Kim SY, McCall SJ, Shen X, Mantyh CR, Hsu DS. Somarelli JA, et al. Among authors: shen x. Mol Cancer Ther. 2020 Dec;19(12):2516-2527. doi: 10.1158/1535-7163.MCT-20-0454. Epub 2020 Nov 6. Mol Cancer Ther. 2020. PMID: 33158998 Free PMC article.
A Tissue Engineering Approach to Metastatic Colon Cancer.
Sarvestani SK, DeHaan RK, Miller PG, Bose S, Shen X, Shuler ML, Huang EH. Sarvestani SK, et al. Among authors: shen x. iScience. 2020 Oct 20;23(11):101719. doi: 10.1016/j.isci.2020.101719. eCollection 2020 Nov 20. iScience. 2020. PMID: 33205026 Free PMC article. Review.
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