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CDC7-independent G1/S transition revealed by targeted protein degradation.
Suski JM, Ratnayeke N, Braun M, Zhang T, Strmiska V, Michowski W, Can G, Simoneau A, Snioch K, Cup M, Sullivan CM, Wu X, Nowacka J, Branigan TB, Pack LR, DeCaprio JA, Geng Y, Zou L, Gygi SP, Walter JC, Meyer T, Sicinski P. Suski JM, et al. Among authors: geng y. Nature. 2022 May;605(7909):357-365. doi: 10.1038/s41586-022-04698-x. Epub 2022 May 4. Nature. 2022. PMID: 35508654 Free PMC article.
G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells.
Liu L, Michowski W, Inuzuka H, Shimizu K, Nihira NT, Chick JM, Li N, Geng Y, Meng AY, Ordureau A, Kołodziejczyk A, Ligon KL, Bronson RT, Polyak K, Harper JW, Gygi SP, Wei W, Sicinski P. Liu L, et al. Among authors: geng y. Nat Cell Biol. 2017 Mar;19(3):177-188. doi: 10.1038/ncb3474. Epub 2017 Feb 13. Nat Cell Biol. 2017. PMID: 28192421 Free PMC article.
The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.
Wang H, Nicolay BN, Chick JM, Gao X, Geng Y, Ren H, Gao H, Yang G, Williams JA, Suski JM, Keibler MA, Sicinska E, Gerdemann U, Haining WN, Roberts TM, Polyak K, Gygi SP, Dyson NJ, Sicinski P. Wang H, et al. Among authors: geng y. Nature. 2017 Jun 15;546(7658):426-430. doi: 10.1038/nature22797. Epub 2017 Jun 7. Nature. 2017. PMID: 28607489 Free PMC article.
Kinase-independent function of E-type cyclins in liver cancer.
Geng Y, Michowski W, Chick JM, Wang YE, Jecrois ME, Sweeney KE, Liu L, Han RC, Ke N, Zagozdzon A, Sicinska E, Bronson RT, Gygi SP, Sicinski P. Geng Y, et al. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1015-1020. doi: 10.1073/pnas.1711477115. Epub 2018 Jan 16. Proc Natl Acad Sci U S A. 2018. PMID: 29339491 Free PMC article.
Cyclin E in normal physiology and disease states.
Chu C, Geng Y, Zhou Y, Sicinski P. Chu C, et al. Among authors: geng y. Trends Cell Biol. 2021 Sep;31(9):732-746. doi: 10.1016/j.tcb.2021.05.001. Epub 2021 May 27. Trends Cell Biol. 2021. PMID: 34052101 Free PMC article. Review.
Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.
Bienvenu F, Jirawatnotai S, Elias JE, Meyer CA, Mizeracka K, Marson A, Frampton GM, Cole MF, Odom DT, Odajima J, Geng Y, Zagozdzon A, Jecrois M, Young RA, Liu XS, Cepko CL, Gygi SP, Sicinski P. Bienvenu F, et al. Among authors: geng y. Nature. 2010 Jan 21;463(7279):374-8. doi: 10.1038/nature08684. Nature. 2010. PMID: 20090754 Free PMC article.
Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo.
Odajima J, Saini S, Jung P, Ndassa-Colday Y, Ficaro S, Geng Y, Marco E, Michowski W, Wang YE, DeCaprio JA, Litovchick L, Marto J, Sicinski P. Odajima J, et al. Among authors: geng y. PLoS Genet. 2016 Nov 9;12(11):e1006429. doi: 10.1371/journal.pgen.1006429. eCollection 2016 Nov. PLoS Genet. 2016. PMID: 27828963 Free PMC article.
Targeting the cyclin-dependent kinase 5 in metastatic melanoma.
Sharma S, Zhang T, Michowski W, Rebecca VW, Xiao M, Ferretti R, Suski JM, Bronson RT, Paulo JA, Frederick D, Fassl A, Boland GM, Geng Y, Lees JA, Medema RH, Herlyn M, Gygi SP, Sicinski P. Sharma S, et al. Among authors: geng y. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8001-8012. doi: 10.1073/pnas.1912617117. Epub 2020 Mar 19. Proc Natl Acad Sci U S A. 2020. PMID: 32193336 Free PMC article.
3,737 results