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Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia.
Laukkanen S, Veloso A, Yan C, Oksa L, Alpert EJ, Do D, Hyvärinen N, McCarthy K, Adhikari A, Yang Q, Iyer S, Garcia SP, Pello A, Ruokoranta T, Moisio S, Adhikari S, Yoder JA, Gallagher K, Whelton L, Allen JR, Jin AH, Loontiens S, Heinäniemi M, Kelliher M, Heckman CA, Lohi O, Langenau DM. Laukkanen S, et al. Among authors: langenau dm. Blood. 2022 Oct 27;140(17):1891-1906. doi: 10.1182/blood.2021015106. Blood. 2022. PMID: 35544598 Free PMC article.
Pten regulates zebrafish hematopoiesis.
Langenau DM. Langenau DM. Blood. 2014 Jan 9;123(2):149-50. doi: 10.1182/blood-2013-11-536136. Blood. 2014. PMID: 24408201 Free article.
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma.
Chen EY, DeRan MT, Ignatius MS, Grandinetti KB, Clagg R, McCarthy KM, Lobbardi RM, Brockmann J, Keller C, Wu X, Langenau DM. Chen EY, et al. Among authors: langenau dm. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5349-54. doi: 10.1073/pnas.1317731111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706870 Free PMC article.
Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish.
Moore FE, Garcia EG, Lobbardi R, Jain E, Tang Q, Moore JC, Cortes M, Molodtsov A, Kasheta M, Luo CC, Garcia AJ, Mylvaganam R, Yoder JA, Blackburn JS, Sadreyev RI, Ceol CJ, North TE, Langenau DM. Moore FE, et al. Among authors: langenau dm. J Exp Med. 2016 May 30;213(6):979-92. doi: 10.1084/jem.20152013. Epub 2016 May 2. J Exp Med. 2016. PMID: 27139488 Free PMC article.
Molecularly distinct models of zebrafish Myc-induced B cell leukemia.
Borga C, Foster CA, Iyer S, Garcia SP, Langenau DM, Frazer JK. Borga C, et al. Among authors: langenau dm. Leukemia. 2019 Feb;33(2):559-562. doi: 10.1038/s41375-018-0328-1. Epub 2018 Dec 20. Leukemia. 2019. PMID: 30573774 Free PMC article. No abstract available.
Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.
Yan C, Brunson DC, Tang Q, Do D, Iftimia NA, Moore JC, Hayes MN, Welker AM, Garcia EG, Dubash TD, Hong X, Drapkin BJ, Myers DT, Phat S, Volorio A, Marvin DL, Ligorio M, Dershowitz L, McCarthy KM, Karabacak MN, Fletcher JA, Sgroi DC, Iafrate JA, Maheswaran S, Dyson NJ, Haber DA, Rawls JF, Langenau DM. Yan C, et al. Among authors: langenau dm. Cell. 2019 Jun 13;177(7):1903-1914.e14. doi: 10.1016/j.cell.2019.04.004. Epub 2019 Apr 25. Cell. 2019. PMID: 31031007 Free PMC article.
96 results