Skiba MA - Search Results

1

Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent C-Methyltransferases.

Lao Y, Skiba MA, Chun SW, Narayan ARH, Smith JL. Lao Y, et al. Among authors: skiba ma. ACS Chem Biol. 2022 Aug 19;17(8):2088-2098. doi: 10.1021/acschembio.2c00085. Epub 2022 May 20. ACS Chem Biol. 2022. PMID: 35594521 Free PMC article.

2

Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase.

Skiba MA, Sikkema AP, Fiers WD, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Skiba MA, et al. ACS Chem Biol. 2016 Dec 16;11(12):3319-3327. doi: 10.1021/acschembio.6b00759. Epub 2016 Oct 18. ACS Chem Biol. 2016. PMID: 27723289 Free PMC article.

3

Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation.

Motl N, Skiba MA, Kabil O, Smith JL, Banerjee R. Motl N, et al. Among authors: skiba ma. J Biol Chem. 2017 Aug 25;292(34):14026-14038. doi: 10.1074/jbc.M117.790170. Epub 2017 Jul 6. J Biol Chem. 2017. PMID: 28684420 Free PMC article.

4

A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.

Skiba MA, Sikkema AP, Moss NA, Tran CL, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Skiba MA, et al. ACS Chem Biol. 2017 Dec 15;12(12):3039-3048. doi: 10.1021/acschembio.7b00746. Epub 2017 Nov 14. ACS Chem Biol. 2017. PMID: 29096064 Free PMC article.

5

Chemistry of a Unique Polyketide-like Synthase.

Chun SW, Hinze ME, Skiba MA, Narayan ARH. Chun SW, et al. Among authors: skiba ma. J Am Chem Soc. 2018 Feb 21;140(7):2430-2433. doi: 10.1021/jacs.7b13297. Epub 2018 Feb 8. J Am Chem Soc. 2018. PMID: 29390180 Free PMC article.

6

Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module.

Skiba MA, Sikkema AP, Moss NA, Lowell AN, Su M, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Skiba MA, et al. ACS Chem Biol. 2018 Jun 15;13(6):1640-1650. doi: 10.1021/acschembio.8b00252. Epub 2018 May 8. ACS Chem Biol. 2018. PMID: 29701944 Free PMC article.

7

PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production.

Skiba MA, Maloney FP, Dan Q, Fraley AE, Aldrich CC, Smith JL, Brown WC. Skiba MA, et al. Methods Enzymol. 2018;604:45-88. doi: 10.1016/bs.mie.2018.01.035. Epub 2018 Mar 16. Methods Enzymol. 2018. PMID: 29779664 Free PMC article.

8

Structural Basis of Polyketide Synthase O-Methylation.

Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Skiba MA, et al. ACS Chem Biol. 2018 Dec 21;13(12):3221-3228. doi: 10.1021/acschembio.8b00687. Epub 2018 Dec 3. ACS Chem Biol. 2018. PMID: 30489068 Free PMC article.

9

Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.

Skiba MA, Tran CL, Dan Q, Sikkema AP, Klaver Z, Gerwick WH, Sherman DH, Smith JL. Skiba MA, et al. Structure. 2020 Jan 7;28(1):63-74.e4. doi: 10.1016/j.str.2019.11.004. Epub 2019 Nov 27. Structure. 2020. PMID: 31785925 Free PMC article.

10

Antibodies expand the scope of angiotensin receptor pharmacology.

Skiba MA, Sterling SM, Rawson S, Zhang S, Xu H, Jiang H, Nemeth GR, Gilman MSA, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Rockman HA, Barth P, Wingler LM, Kruse AC. Skiba MA, et al. Nat Chem Biol. 2024 May 14. doi: 10.1038/s41589-024-01620-6. Online ahead of print. Nat Chem Biol. 2024. PMID: 38744986

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