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Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure With Reduced Ejection Fraction: DEFINE-HF.
Selvaraj S, Fu Z, Jones P, Kwee LC, Windsor SL, Ilkayeva O, Newgard CB, Margulies KB, Husain M, Inzucchi SE, McGuire DK, Pitt B, Scirica BM, Lanfear DE, Nassif ME, Javaheri A, Mentz RJ, Kosiborod MN, Shah SH; DEFINE-HF Investigators. Selvaraj S, et al. Among authors: newgard cb. Circulation. 2022 Sep 13;146(11):808-818. doi: 10.1161/CIRCULATIONAHA.122.060402. Epub 2022 May 23. Circulation. 2022. PMID: 35603596 Free PMC article.
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.
Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, Muoio DM. Koves TR, et al. Among authors: newgard cb. J Biol Chem. 2005 Sep 30;280(39):33588-98. doi: 10.1074/jbc.M507621200. Epub 2005 Aug 3. J Biol Chem. 2005. PMID: 16079133 Free article.
Glucose metabolism as a target of histone deacetylase inhibitors.
Wardell SE, Ilkayeva OR, Wieman HL, Frigo DE, Rathmell JC, Newgard CB, McDonnell DP. Wardell SE, et al. Among authors: newgard cb. Mol Endocrinol. 2009 Mar;23(3):388-401. doi: 10.1210/me.2008-0179. Epub 2008 Dec 23. Mol Endocrinol. 2009. PMID: 19106193 Free PMC article.
Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.
Turer AT, Stevens RD, Bain JR, Muehlbauer MJ, van der Westhuizen J, Mathew JP, Schwinn DA, Glower DD, Newgard CB, Podgoreanu MV. Turer AT, et al. Among authors: newgard cb. Circulation. 2009 Apr 7;119(13):1736-46. doi: 10.1161/CIRCULATIONAHA.108.816116. Epub 2009 Mar 23. Circulation. 2009. PMID: 19307475 Free PMC article.
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.
Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, Lien LF, Haqq AM, Shah SH, Arlotto M, Slentz CA, Rochon J, Gallup D, Ilkayeva O, Wenner BR, Yancy WS Jr, Eisenson H, Musante G, Surwit RS, Millington DS, Butler MD, Svetkey LP. Newgard CB, et al. Cell Metab. 2009 Apr;9(4):311-26. doi: 10.1016/j.cmet.2009.02.002. Cell Metab. 2009. PMID: 19356713 Free PMC article.
411 results