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Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses.
McNaughton AL, Paton RS, Edmans M, Youngs J, Wellens J, Phalora P, Fyfe A, Belij-Rammerstorfer S, Bolton JS, Ball J, Carnell GW, Dejnirattisai W, Dold C, Eyre DW, Hopkins P, Howarth A, Kooblall K, Klim H, Leaver S, Lee LN, López-Camacho C, Lumley SF, Macallan DC, Mentzer AJ, Provine NM, Ratcliff J, Slon-Compos J, Skelly D, Stolle L, Supasa P, Temperton N, Walker C, Wang B, Wyncoll D; Oxford Protective T Cell Immunology for COVID-19 (OPTIC) consortium; Scottish National Blood Transfusion Service (SNBTS) consortium; Simmonds P, Lambe T, Baillie JK, Semple MG, Openshaw PJ; International Severe Acute Respiratory and emerging Infection Consortium Coronavirus Clinical Characterisation Consortium (ISARIC4C) investigators; Obolski U, Turner M, Carroll M, Mongkolsapaya J, Screaton G, Kennedy SH, Jarvis L, Barnes E, Dunachie S, Lourenço J, Matthews PC, Bicanic T, Klenerman P, Gupta S, Thompson CP. McNaughton AL, et al. Among authors: wyncoll d. JCI Insight. 2022 Jul 8;7(13):e156372. doi: 10.1172/jci.insight.156372. JCI Insight. 2022. PMID: 35608920 Free PMC article.
Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients.
Youngs J, Provine NM, Lim N, Sharpe HR, Amini A, Chen YL, Luo J, Edmans MD, Zacharopoulou P, Chen W, Sampson O, Paton R, Hurt WJ, Duncan DA, McNaughton AL, Miao VN, Leaver S, Wyncoll DLA, Ball J, Hopkins P; Oxford Immunology Network Covid-19 response T cell Consortium; Oxford Protective T cell Immunology for COVID-19 (OPTIC) Clinical team; Skelly DT, Barnes E, Dunachie S, Ogg G, Lambe T, Pavord I, Shalek AK, Thompson CP, Xue L, Macallan DC, Goulder P, Klenerman P, Bicanic T. Youngs J, et al. Among authors: wyncoll dla. PLoS Pathog. 2021 Sep 16;17(9):e1009804. doi: 10.1371/journal.ppat.1009804. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34529726 Free PMC article.
Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units.
Charalampous T, Alcolea-Medina A, Snell LB, Williams TGS, Batra R, Alder C, Telatin A, Camporota L, Meadows CIS, Wyncoll D, Barrett NA, Hemsley CJ, Bryan L, Newsholme W, Boyd SE, Green A, Mahadeva U, Patel A, Cliff PR, Page AJ, O'Grady J, Edgeworth JD. Charalampous T, et al. Among authors: wyncoll d. Genome Med. 2021 Nov 17;13(1):182. doi: 10.1186/s13073-021-00991-y. Genome Med. 2021. PMID: 34784976 Free PMC article.
Costs and quality of life associated with acute upper gastrointestinal bleeding in the UK: cohort analysis of patients in a cluster randomised trial.
Campbell HE, Stokes EA, Bargo D, Logan RF, Mora A, Hodge R, Gray A, James MW, Stanley AJ, Everett SM, Bailey AA, Dallal H, Greenaway J, Dyer C, Llewelyn C, Walsh TS, Travis SP, Murphy MF, Jairath V; TRIGGER investigators. Campbell HE, et al. BMJ Open. 2015 Apr 29;5(4):e007230. doi: 10.1136/bmjopen-2014-007230. BMJ Open. 2015. PMID: 25926146 Free PMC article. Clinical Trial.
Tracheostomy, ventilatory wean, and decannulation in COVID-19 patients.
Tornari C, Surda P, Takhar A, Amin N, Dinham A, Harding R, Ranford DA, Archer SK, Wyncoll D, Tricklebank S, Ahmad I, Simo R, Arora A. Tornari C, et al. Among authors: wyncoll d. Eur Arch Otorhinolaryngol. 2021 May;278(5):1595-1604. doi: 10.1007/s00405-020-06187-1. Epub 2020 Aug 1. Eur Arch Otorhinolaryngol. 2021. PMID: 32740720 Free PMC article.
Development and evaluation of a nanopore 16S rRNA gene sequencing service for same day targeted treatment of bacterial respiratory infection in the intensive care unit.
Baldan R, Cliff PR, Burns S, Medina A, Smith GC, Batra R, Cerda A, Wilson R, Merrill T, Lewis SJ, Patel A, Jeyaratnam D, Wyncoll DL, Barrett N, Chand MA, Edgeworth JD. Baldan R, et al. Among authors: wyncoll dl. J Infect. 2021 Aug;83(2):167-174. doi: 10.1016/j.jinf.2021.06.014. Epub 2021 Jun 17. J Infect. 2021. PMID: 34146598
136 results