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CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis.
Nat Microbiol. 2022 Jun;7(6):766-779. doi: 10.1038/s41564-022-01130-y. Epub 2022 May 30.
Nat Microbiol. 2022.
PMID: 35637331
Free PMC article.
Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis.
Poulton NC, Azadian ZA, DeJesus MA, Rock JM.
Poulton NC, et al. Among authors: azadian za.
Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0090422. doi: 10.1128/aac.00904-22. Epub 2022 Aug 3.
Antimicrob Agents Chemother. 2022.
PMID: 35920665
Free PMC article.
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Compensatory evolution in NusG improves fitness of drug-resistant M. tuberculosis.
Eckartt KA, Delbeau M, Munsamy-Govender V, DeJesus MA, Azadian ZA, Reddy AK, Chandanani J, Poulton NC, Quiñones-Garcia S, Bosch B, Landick R, Campbell EA, Rock JM.
Eckartt KA, et al. Among authors: azadian za.
Nature. 2024 Apr;628(8006):186-194. doi: 10.1038/s41586-024-07206-5. Epub 2024 Mar 20.
Nature. 2024.
PMID: 38509362
Free PMC article.
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Beyond antibiotic resistance: The whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria.
Poulton NC, DeJesus MA, Munsamy-Govender V, Kanai M, Roberts CG, Azadian ZA, Bosch B, Lin KM, Li S, Rock JM.
Poulton NC, et al. Among authors: azadian za.
Cell Chem Biol. 2024 Apr 18;31(4):669-682.e7. doi: 10.1016/j.chembiol.2023.12.020. Epub 2024 Jan 23.
Cell Chem Biol. 2024.
PMID: 38266648
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Beyond antibiotic resistance: the whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria.
Poulton NC, DeJesus MA, Munsamy-Govender V, Roberts CG, Azadian ZA, Bosch B, Lin KM, Li S, Rock JM.
Poulton NC, et al. Among authors: azadian za.
bioRxiv [Preprint]. 2023 Jun 5:2023.06.02.543512. doi: 10.1101/2023.06.02.543512.
bioRxiv. 2023.
PMID: 37333137
Free PMC article.
Updated.
Preprint.
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