Schnappinger D - Search Results

1

CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis.

Li S, Poulton NC, Chang JS, Azadian ZA, DeJesus MA, Ruecker N, Zimmerman MD, Eckartt KA, Bosch B, Engelhart CA, Sullivan DF, Gengenbacher M, Dartois VA, Schnappinger D, Rock JM. Li S, et al. Among authors: schnappinger d. Nat Microbiol. 2022 Jun;7(6):766-779. doi: 10.1038/s41564-022-01130-y. Epub 2022 May 30. Nat Microbiol. 2022. PMID: 35637331 Free PMC article.

2

In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice.

Gandotra S, Schnappinger D, Monteleone M, Hillen W, Ehrt S. Gandotra S, et al. Among authors: schnappinger d. Nat Med. 2007 Dec;13(12):1515-20. doi: 10.1038/nm1683. Epub 2007 Dec 2. Nat Med. 2007. PMID: 18059281 Free PMC article.

3

A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis.

Vandal OH, Pierini LM, Schnappinger D, Nathan CF, Ehrt S. Vandal OH, et al. Among authors: schnappinger d. Nat Med. 2008 Aug;14(8):849-54. doi: 10.1038/nm.1795. Epub 2008 Jul 20. Nat Med. 2008. PMID: 18641659 Free PMC article.

4

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.

Barry CE 3rd, Boshoff HI, Dartois V, Dick T, Ehrt S, Flynn J, Schnappinger D, Wilkinson RJ, Young D. Barry CE 3rd, et al. Among authors: schnappinger d. Nat Rev Microbiol. 2009 Dec;7(12):845-55. doi: 10.1038/nrmicro2236. Epub 2009 Oct 26. Nat Rev Microbiol. 2009. PMID: 19855401 Free PMC article. Review.

5

Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.

Rhee KY, de Carvalho LP, Bryk R, Ehrt S, Marrero J, Park SW, Schnappinger D, Venugopal A, Nathan C. Rhee KY, et al. Among authors: schnappinger d. Trends Microbiol. 2011 Jul;19(7):307-14. doi: 10.1016/j.tim.2011.03.008. Epub 2011 May 10. Trends Microbiol. 2011. PMID: 21561773 Free PMC article.

6

Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.

Woong Park S, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE 3rd, Aldrich CC, Ehrt S, Schnappinger D. Woong Park S, et al. Among authors: schnappinger d. PLoS Pathog. 2011 Sep;7(9):e1002264. doi: 10.1371/journal.ppat.1002264. Epub 2011 Sep 29. PLoS Pathog. 2011. PMID: 21980288 Free PMC article.

7

Genetic Approaches to Facilitate Antibacterial Drug Development.

Schnappinger D. Schnappinger D. Cold Spring Harb Perspect Med. 2015 Feb 13;5(7):a021139. doi: 10.1101/cshperspect.a021139. Cold Spring Harb Perspect Med. 2015. PMID: 25680982 Free PMC article. Review.

8

A broader spectrum of tuberculosis.

Schnappinger D, Ehrt S. Schnappinger D, et al. Nat Med. 2016 Oct 6;22(10):1076-1077. doi: 10.1038/nm.4186. Nat Med. 2016. PMID: 27711059 No abstract available.

9

Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis.

DeJesus MA, Gerrick ER, Xu W, Park SW, Long JE, Boutte CC, Rubin EJ, Schnappinger D, Ehrt S, Fortune SM, Sassetti CM, Ioerger TR. DeJesus MA, et al. Among authors: schnappinger d. mBio. 2017 Jan 17;8(1):e02133-16. doi: 10.1128/mBio.02133-16. mBio. 2017. PMID: 28096490 Free PMC article.

10

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.

Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM. Rock JM, et al. Among authors: schnappinger d. Nat Microbiol. 2017 Feb 6;2:16274. doi: 10.1038/nmicrobiol.2016.274. Nat Microbiol. 2017. PMID: 28165460 Free PMC article.

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