Cai Z - Search Results

1

Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q.

Spurrier J, Nicholson L, Fang XT, Stoner AJ, Toyonaga T, Holden D, Siegert TR, Laird W, Allnutt MA, Chiasseu M, Brody AH, Takahashi H, Nies SH, Pérez-Cañamás A, Sadasivam P, Lee S, Li S, Zhang L, Huang YH, Carson RE, Cai Z, Strittmatter SM. Spurrier J, et al. Among authors: cai z. Sci Transl Med. 2022 Jun;14(647):eabi8593. doi: 10.1126/scitranslmed.abi8593. Epub 2022 Jun 1. Sci Transl Med. 2022. PMID: 35648810 Free PMC article.

2

Fluorine-18-Labeled Antagonist for PET Imaging of Kappa Opioid Receptors.

Cai Z, Li S, Pracitto R, Navarro A, Shirali A, Ropchan J, Huang Y. Cai Z, et al. ACS Chem Neurosci. 2017 Jan 18;8(1):12-16. doi: 10.1021/acschemneuro.6b00268. Epub 2016 Oct 20. ACS Chem Neurosci. 2017. PMID: 27741398

3

PET Imaging Evaluation of Four σ₁ Radiotracers in Nonhuman Primates.

Baum E, Cai Z, Bois F, Holden D, Lin SF, Lara-Jaime T, Kapinos M, Chen Y, Deuther-Conrad W, Fischer S, Dukic-Stefanovic S, Bunse P, Wünsch B, Brust P, Jia H, Huang Y. Baum E, et al. Among authors: cai z. J Nucl Med. 2017 Jun;58(6):982-988. doi: 10.2967/jnumed.116.188052. Epub 2017 Feb 23. J Nucl Med. 2017. PMID: 28232607 Free article.

4

PET Imaging for Early Detection of Alzheimer's Disease: From Pathologic to Physiologic Biomarkers.

Bao W, Jia H, Finnema S, Cai Z, Carson RE, Huang YH. Bao W, et al. Among authors: cai z. PET Clin. 2017 Jul;12(3):329-350. doi: 10.1016/j.cpet.2017.03.001. Epub 2017 May 2. PET Clin. 2017. PMID: 28576171 Review.

5

Novel ¹⁸F-Labeled κ-Opioid Receptor Antagonist as PET Radiotracer: Synthesis and In Vivo Evaluation of ¹⁸F-LY2459989 in Nonhuman Primates.

Li S, Cai Z, Zheng MQ, Holden D, Naganawa M, Lin SF, Ropchan J, Labaree D, Kapinos M, Lara-Jaime T, Navarro A, Huang Y. Li S, et al. Among authors: cai z. J Nucl Med. 2018 Jan;59(1):140-146. doi: 10.2967/jnumed.117.195586. Epub 2017 Jul 26. J Nucl Med. 2018. PMID: 28747521 Free PMC article.

6

PET imaging of synaptic density: A new tool for investigation of neuropsychiatric diseases.

Cai Z, Li S, Matuskey D, Nabulsi N, Huang Y. Cai Z, et al. Neurosci Lett. 2019 Jan 19;691:44-50. doi: 10.1016/j.neulet.2018.07.038. Epub 2018 Jul 31. Neurosci Lett. 2019. PMID: 30075287 Free PMC article. Review.

7

Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates.

Li S, Cai Z, Wu X, Holden D, Pracitto R, Kapinos M, Gao H, Labaree D, Nabulsi N, Carson RE, Huang Y. Li S, et al. Among authors: cai z. ACS Chem Neurosci. 2019 Mar 20;10(3):1544-1554. doi: 10.1021/acschemneuro.8b00526. Epub 2018 Nov 16. ACS Chem Neurosci. 2019. PMID: 30396272 Free PMC article.

8

A Novel ¹⁸F-Labeled Radioligand for Positron Emission Tomography Imaging of 11β-Hydroxysteroid Dehydrogenase (11β-HSD1): Synthesis and Preliminary Evaluation in Nonhuman Primates.

Baum E, Zhang W, Li S, Cai Z, Holden D, Huang Y. Baum E, et al. Among authors: cai z. ACS Chem Neurosci. 2019 May 15;10(5):2450-2458. doi: 10.1021/acschemneuro.8b00715. Epub 2019 Feb 19. ACS Chem Neurosci. 2019. PMID: 30689943

9

First in-human PET study and kinetic evaluation of [¹⁸F]AS2471907 for imaging 11β-hydroxysteroid dehydrogenase type 1.

Bhatt S, Nabulsi NB, Li S, Cai Z, Matuskey D, Bini J, Najafzadeh S, Kapinos M, Ropchan JR, Carson RE, Cosgrove KP, Huang Y, Hillmer AT. Bhatt S, et al. Among authors: cai z. J Cereb Blood Flow Metab. 2020 Apr;40(4):695-704. doi: 10.1177/0271678X19838633. Epub 2019 Mar 21. J Cereb Blood Flow Metab. 2020. PMID: 30895878 Free PMC article.

10

In Vivo Synaptic Density Imaging with ¹¹C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease.

Toyonaga T, Smith LM, Finnema SJ, Gallezot JD, Naganawa M, Bini J, Mulnix T, Cai Z, Ropchan J, Huang Y, Strittmatter SM, Carson RE. Toyonaga T, et al. Among authors: cai z. J Nucl Med. 2019 Dec;60(12):1780-1786. doi: 10.2967/jnumed.118.223867. Epub 2019 May 17. J Nucl Med. 2019. PMID: 31101744 Free PMC article.

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