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Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q.
Spurrier J, Nicholson L, Fang XT, Stoner AJ, Toyonaga T, Holden D, Siegert TR, Laird W, Allnutt MA, Chiasseu M, Brody AH, Takahashi H, Nies SH, Pérez-Cañamás A, Sadasivam P, Lee S, Li S, Zhang L, Huang YH, Carson RE, Cai Z, Strittmatter SM. Spurrier J, et al. Among authors: perez canamas a. Sci Transl Med. 2022 Jun;14(647):eabi8593. doi: 10.1126/scitranslmed.abi8593. Epub 2022 Jun 1. Sci Transl Med. 2022. PMID: 35648810 Free PMC article.
Adeno-associated viral vector serotype 9-based gene therapy for Niemann-Pick disease type A.
Samaranch L, Pérez-Cañamás A, Soto-Huelin B, Sudhakar V, Jurado-Arjona J, Hadaczek P, Ávila J, Bringas JR, Casas J, Chen H, He X, Schuchman EH, Cheng SH, Forsayeth J, Bankiewicz KS, Ledesma MD. Samaranch L, et al. Among authors: perez canamas a. Sci Transl Med. 2019 Aug 21;11(506):eaat3738. doi: 10.1126/scitranslmed.aat3738. Sci Transl Med. 2019. PMID: 31434754 Free PMC article.
Prion protein accumulation in lipid rafts of mouse aging brain.
Agostini F, Dotti CG, Pérez-Cañamás A, Ledesma MD, Benetti F, Legname G. Agostini F, et al. Among authors: perez canamas a. PLoS One. 2013 Sep 10;8(9):e74244. doi: 10.1371/journal.pone.0074244. eCollection 2013. PLoS One. 2013. PMID: 24040215 Free PMC article.