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Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q.
Sci Transl Med. 2022 Jun;14(647):eabi8593. doi: 10.1126/scitranslmed.abi8593. Epub 2022 Jun 1.
Sci Transl Med. 2022.
PMID: 35648810
Free PMC article.
Identifying Loop-Mediated Protein-Protein Interactions Using LoopFinder.
Siegert TR, Bird M, Kritzer JA.
Siegert TR, et al.
Methods Mol Biol. 2017;1561:255-277. doi: 10.1007/978-1-4939-6798-8_15.
Methods Mol Biol. 2017.
PMID: 28236243
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Analysis of Loops that Mediate Protein-Protein Interactions and Translation into Submicromolar Inhibitors.
Siegert TR, Bird MJ, Makwana KM, Kritzer JA.
Siegert TR, et al.
J Am Chem Soc. 2016 Oct 5;138(39):12876-12884. doi: 10.1021/jacs.6b05656. Epub 2016 Sep 21.
J Am Chem Soc. 2016.
PMID: 27611902
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Conformational Restriction of Peptides Using Dithiol Bis-Alkylation.
Peraro L, Siegert TR, Kritzer JA.
Peraro L, et al. Among authors: siegert tr.
Methods Enzymol. 2016;580:303-32. doi: 10.1016/bs.mie.2016.05.035. Epub 2016 Jun 24.
Methods Enzymol. 2016.
PMID: 27586339
Free PMC article.
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Comprehensive analysis of loops at protein-protein interfaces for macrocycle design.
Gavenonis J, Sheneman BA, Siegert TR, Eshelman MR, Kritzer JA.
Gavenonis J, et al. Among authors: siegert tr.
Nat Chem Biol. 2014 Sep;10(9):716-22. doi: 10.1038/nchembio.1580. Epub 2014 Jul 20.
Nat Chem Biol. 2014.
PMID: 25038791
Free PMC article.
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