Aplin AE - Search Results

1

A Genome-Wide Screen Identifies PDPK1 as a Target to Enhance the Efficacy of MEK1/2 Inhibitors in NRAS Mutant Melanoma.

Cai W, Nguyen MQ, Wilski NA, Purwin TJ, Vernon M, Tiago M, Aplin AE. Cai W, et al. Among authors: aplin ae. Cancer Res. 2022 Jul 18;82(14):2625-2639. doi: 10.1158/0008-5472.CAN-21-3217. Cancer Res. 2022. PMID: 35657206 Free PMC article.

2

Rnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensions.

Klein RM, Aplin AE. Klein RM, et al. Among authors: aplin ae. Cancer Res. 2009 Mar 15;69(6):2224-33. doi: 10.1158/0008-5472.CAN-08-3201. Epub 2009 Feb 24. Cancer Res. 2009. PMID: 19244113 Free PMC article.

3

Mcl-1 is required for melanoma cell resistance to anoikis.

Boisvert-Adamo K, Longmate W, Abel EV, Aplin AE. Boisvert-Adamo K, et al. Among authors: aplin ae. Mol Cancer Res. 2009 Apr;7(4):549-56. doi: 10.1158/1541-7786.MCR-08-0358. Mol Cancer Res. 2009. PMID: 19372583 Free PMC article.

4

alphaB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells.

Hu R, Aplin AE. Hu R, et al. Among authors: aplin ae. Pigment Cell Melanoma Res. 2010 Apr;23(2):201-9. doi: 10.1111/j.1755-148X.2010.00668.x. Epub 2010 Jan 7. Pigment Cell Melanoma Res. 2010. PMID: 20067552 Free PMC article.

5

FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells.

Abel EV, Aplin AE. Abel EV, et al. Among authors: aplin ae. Cancer Res. 2010 Apr 1;70(7):2891-900. doi: 10.1158/0008-5472.CAN-09-3139. Epub 2010 Mar 23. Cancer Res. 2010. PMID: 20332228 Free PMC article.

6

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

Shao Y, Aplin AE. Shao Y, et al. Among authors: aplin ae. Cancer Res. 2010 Aug 15;70(16):6670-81. doi: 10.1158/0008-5472.CAN-09-4471. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647317 Free PMC article.

7

CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway.

Trimmer C, Whitaker-Menezes D, Bonuccelli G, Milliman JN, Daumer KM, Aplin AE, Pestell RG, Sotgia F, Lisanti MP, Capozza F. Trimmer C, et al. Among authors: aplin ae. Cancer Res. 2010 Oct 1;70(19):7489-99. doi: 10.1158/0008-5472.CAN-10-0900. Epub 2010 Aug 13. Cancer Res. 2010. PMID: 20709760 Free PMC article.

8

Hyperactivation of MEK-ERK1/2 signaling and resistance to apoptosis induced by the oncogenic B-RAF inhibitor, PLX4720, in mutant N-RAS melanoma cells.

Kaplan FM, Shao Y, Mayberry MM, Aplin AE. Kaplan FM, et al. Among authors: aplin ae. Oncogene. 2011 Jan 20;30(3):366-71. doi: 10.1038/onc.2010.408. Epub 2010 Sep 6. Oncogene. 2011. PMID: 20818433 Free PMC article.

9

FOXD3 regulates migration properties and Rnd3 expression in melanoma cells.

Katiyar P, Aplin AE. Katiyar P, et al. Among authors: aplin ae. Mol Cancer Res. 2011 May;9(5):545-52. doi: 10.1158/1541-7786.MCR-10-0454. Epub 2011 Apr 8. Mol Cancer Res. 2011. PMID: 21478267 Free PMC article.

10

Mechanisms of resistance to RAF inhibitors in melanoma.

Aplin AE, Kaplan FM, Shao Y. Aplin AE, et al. J Invest Dermatol. 2011 Sep;131(9):1817-20. doi: 10.1038/jid.2011.147. Epub 2011 May 19. J Invest Dermatol. 2011. PMID: 21593776 Free PMC article. Review.

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