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INA03, a potent transferrin-competitive antibody-drug conjugate against CD71, for a safer acute leukemia treatment.
Bratti M, Stubbs E, Kolodych S, Souchet H, Kelly L, Merlin J, Marchal M, Castellano R, Josselin E, Pasquer H, Benajiba L, Puissant A, Koniev O, Collette Y, Belanger C, Hermine O, Monteiro RC, Launay P. Bratti M, et al. Among authors: castellano r. Mol Cancer Ther. 2024 Apr 20. doi: 10.1158/1535-7163.MCT-23-0548. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38641421
DR5 disulfide bonding as a sensor and effector of protein folding stress.
Law ME, Dulloo ZM, Eggleston SR, Takacs GP, Alexandrow GM, Wang M, Su H, Forsyth B, Chiang CW, Sharma A, Kanumuri SRR, Guryanova OA, Harrison JK, Tirosh B, Castellano RK, Law BK. Law ME, et al. Among authors: castellano rk. bioRxiv [Preprint]. 2024 Mar 7:2024.03.04.583390. doi: 10.1101/2024.03.04.583390. bioRxiv. 2024. PMID: 38496520 Free PMC article. Preprint.
mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema.
Lipskaia L, Breau M, Cayrou C, Churikov D, Braud L, Jacquet J, Born E, Fouillade C, Curras-Alonso S, Bauwens S, Jourquin F, Fiore F, Castellano R, Josselin E, Sánchez-Ferrer C, Giovinazzo G, Lachaud C, Gilson E, Flores I, Londono-Vallejo A, Adnot S, Géli V. Lipskaia L, et al. Among authors: castellano r. EMBO Rep. 2024 Mar;25(3):1650-1684. doi: 10.1038/s44319-023-00041-1. Epub 2024 Feb 29. EMBO Rep. 2024. PMID: 38424230 Free PMC article.
Downregulation of stromal syntenin sustains AML development.
Leblanc R, Ghossoub R, Goubard A, Castellano R, Fares J, Camoin L, Audebert S, Balzano M, Bou-Tayeh B, Fauriat C, Vey N, Garciaz S, Borg JP, Collette Y, Aurrand-Lions M, David G, Zimmermann P. Leblanc R, et al. Among authors: castellano r. EMBO Mol Med. 2023 Nov 8;15(11):e17570. doi: 10.15252/emmm.202317570. Epub 2023 Oct 11. EMBO Mol Med. 2023. PMID: 37819151 Free PMC article.
A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells.
Berrada S, Martínez-Balsalobre E, Larcher L, Azzoni V, Vasquez N, Da Costa M, Abel S, Audoly G, Lee L, Montersino C, Castellano R, Combes S, Gelot C, Ceccaldi R, Guervilly JH, Soulier J, Lachaud C. Berrada S, et al. Among authors: castellano r. Nucleic Acids Res. 2023 Aug 25;51(15):7988-8004. doi: 10.1093/nar/gkad559. Nucleic Acids Res. 2023. PMID: 37395445 Free PMC article.
168 results