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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS. Replogle JM, et al. Among authors: guna a. Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9. Cell. 2022. PMID: 35688146 Free PMC article.
Macromolecular condensation buffers intracellular water potential.
Watson JL, Seinkmane E, Styles CT, Mihut A, Krüger LK, McNally KE, Planelles-Herrero VJ, Dudek M, McCall PM, Barbiero S, Vanden Oever M, Peak-Chew SY, Porebski BT, Zeng A, Rzechorzek NM, Wong DCS, Beale AD, Stangherlin A, Riggi M, Iwasa J, Morf J, Miliotis C, Guna A, Inglis AJ, Brugués J, Voorhees RM, Chambers JE, Meng QJ, O'Neill JS, Edgar RS, Derivery E. Watson JL, et al. Among authors: guna a. Nature. 2023 Nov;623(7988):842-852. doi: 10.1038/s41586-023-06626-z. Epub 2023 Oct 18. Nature. 2023. PMID: 37853127 Free PMC article.
MTCH2 is a mitochondrial outer membrane protein insertase.
Guna A, Stevens TA, Inglis AJ, Replogle JM, Esantsi TK, Muthukumar G, Shaffer KCL, Wang ML, Pogson AN, Jones JJ, Lomenick B, Chou TF, Weissman JS, Voorhees RM. Guna A, et al. Science. 2022 Oct 21;378(6617):317-322. doi: 10.1126/science.add1856. Epub 2022 Oct 20. Science. 2022. PMID: 36264797 Free PMC article.
Coupled protein quality control during nonsense-mediated mRNA decay.
Inglis AJ, Guna A, Gálvez-Merchán Á, Pal A, Esantsi TK, Keys HR, Frenkel EM, Oania R, Weissman JS, Voorhees RM. Inglis AJ, et al. Among authors: guna a. J Cell Sci. 2023 May 15;136(10):jcs261216. doi: 10.1242/jcs.261216. Epub 2023 May 23. J Cell Sci. 2023. PMID: 37218462 Free PMC article.
WNK1 is an assembly factor for the human ER membrane protein complex.
Pleiner T, Hazu M, Tomaleri GP, Januszyk K, Oania RS, Sweredoski MJ, Moradian A, Guna A, Voorhees RM. Pleiner T, et al. Among authors: guna a. Mol Cell. 2021 Jul 1;81(13):2693-2704.e12. doi: 10.1016/j.molcel.2021.04.013. Epub 2021 May 7. Mol Cell. 2021. PMID: 33964204 Free PMC article.
23 results