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A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection.
Lawrence SP, Elser SE, Torben W, Blair RV, Pahar B, Aye PP, Schiro F, Szeltner D, Doyle-Meyers LA, Haggarty BS, Jordan APO, Romano J, Leslie GJ, Alvarez X, O'Connor DH, Wiseman RW, Fennessey CM, Li Y, Piatak M Jr, Lifson JD, LaBranche CC, Lackner AA, Keele BF, Maness NJ, Marsh M, Hoxie JA. Lawrence SP, et al. Among authors: keele bf. PLoS Pathog. 2022 Jun 17;18(6):e1010507. doi: 10.1371/journal.ppat.1010507. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35714165 Free PMC article.
Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge.
Wilson NA, Keele BF, Reed JS, Piaskowski SM, MacNair CE, Bett AJ, Liang X, Wang F, Thoryk E, Heidecker GJ, Citron MP, Huang L, Lin J, Vitelli S, Ahn CD, Kaizu M, Maness NJ, Reynolds MR, Friedrich TC, Loffredo JT, Rakasz EG, Erickson S, Allison DB, Piatak M Jr, Lifson JD, Shiver JW, Casimiro DR, Shaw GM, Hahn BH, Watkins DI. Wilson NA, et al. Among authors: keele bf. J Virol. 2009 Jul;83(13):6508-21. doi: 10.1128/JVI.00272-09. Epub 2009 Apr 29. J Virol. 2009. PMID: 19403685 Free PMC article.
High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.
Li H, Bar KJ, Wang S, Decker JM, Chen Y, Sun C, Salazar-Gonzalez JF, Salazar MG, Learn GH, Morgan CJ, Schumacher JE, Hraber P, Giorgi EE, Bhattacharya T, Korber BT, Perelson AS, Eron JJ, Cohen MS, Hicks CB, Haynes BF, Markowitz M, Keele BF, Hahn BH, Shaw GM. Li H, et al. Among authors: keele bf. PLoS Pathog. 2010 May 13;6(5):e1000890. doi: 10.1371/journal.ppat.1000890. PLoS Pathog. 2010. PMID: 20485520 Free PMC article.
Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections.
Gnanakaran S, Bhattacharya T, Daniels M, Keele BF, Hraber PT, Lapedes AS, Shen T, Gaschen B, Krishnamoorthy M, Li H, Decker JM, Salazar-Gonzalez JF, Wang S, Jiang C, Gao F, Swanstrom R, Anderson JA, Ping LH, Cohen MS, Markowitz M, Goepfert PA, Saag MS, Eron JJ, Hicks CB, Blattner WA, Tomaras GD, Asmal M, Letvin NL, Gilbert PB, Decamp AC, Magaret CA, Schief WR, Ban YE, Zhang M, Soderberg KA, Sodroski JG, Haynes BF, Shaw GM, Hahn BH, Korber B. Gnanakaran S, et al. Among authors: keele bf. PLoS Pathog. 2011 Sep;7(9):e1002209. doi: 10.1371/journal.ppat.1002209. Epub 2011 Sep 29. PLoS Pathog. 2011. PMID: 21980282 Free PMC article. Clinical Trial.
Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.
Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW Jr, Nagashima K, Keele BF, Macallister R, Smedley J, Pathak VK, Kewalramani VN, Coffin JM, Lifson JD. Del Prete GQ, et al. Among authors: keele bf. J Virol. 2012 Mar;86(6):3152-66. doi: 10.1128/JVI.06886-11. Epub 2012 Jan 11. J Virol. 2012. PMID: 22238316 Free PMC article.
Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies.
Gautam R, Nishimura Y, Lee WR, Donau O, Buckler-White A, Shingai M, Sadjadpour R, Schmidt SD, LaBranche CC, Keele BF, Montefiori D, Mascola JR, Martin MA. Gautam R, et al. Among authors: keele bf. J Virol. 2012 Aug;86(16):8516-26. doi: 10.1128/JVI.00644-12. Epub 2012 May 30. J Virol. 2012. PMID: 22647691 Free PMC article.
Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression.
Breed MW, Jordan AP, Aye PP, Lichtveld CF, Midkiff CC, Schiro FR, Haggarty BS, Sugimoto C, Alvarez X, Sandler NG, Douek DC, Kuroda MJ, Pahar B, Piatak M Jr, Lifson JD, Keele BF, Hoxie JA, Lackner AA. Breed MW, et al. Among authors: keele bf. J Virol. 2013 Feb;87(3):1528-43. doi: 10.1128/JVI.01928-12. Epub 2012 Nov 14. J Virol. 2013. PMID: 23152518 Free PMC article.
206 results