Yang X - Search Results

1

Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-β blockade in HPV-unrelated head and neck cancer.

Redman JM, Friedman J, Robbins Y, Sievers C, Yang X, Lassoued W, Sinkoe A, Papanicolau-Sengos A, Lee CC, Marte JL, Turkbey E, Mydlarz W, Joshi A, London NR Jr, Pierce M, Taylor R, Hong S, Nguyen A, Soon-Shiong P, Schlom J, Gulley JL, Allen CT. Redman JM, et al. Among authors: yang x. J Clin Invest. 2022 Sep 15;132(18):e161400. doi: 10.1172/JCI161400. J Clin Invest. 2022. PMID: 35727629 Free PMC article. Clinical Trial.

2

Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-kappaB and other signal transcription factors in head and neck squamous cell carcinoma.

Yan B, Yang X, Lee TL, Friedman J, Tang J, Van Waes C, Chen Z. Yan B, et al. Among authors: yang x. Genome Biol. 2007;8(5):R78. doi: 10.1186/gb-2007-8-5-r78. Genome Biol. 2007. PMID: 17498291 Free PMC article.

3

A novel nuclear factor-kappaB gene signature is differentially expressed in head and neck squamous cell carcinomas in association with TP53 status.

Lee TL, Yang XP, Yan B, Friedman J, Duggal P, Bagain L, Dong G, Yeh NT, Wang J, Zhou J, Elkahloun A, Van Waes C, Chen Z. Lee TL, et al. Clin Cancer Res. 2007 Oct 1;13(19):5680-91. doi: 10.1158/1078-0432.CCR-07-0670. Clin Cancer Res. 2007. PMID: 17908957

4

Deficient TP53 expression, function, and cisplatin sensitivity are restored by quinacrine in head and neck cancer.

Friedman J, Nottingham L, Duggal P, Pernas FG, Yan B, Yang XP, Chen Z, Van Waes C. Friedman J, et al. Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6568-78. doi: 10.1158/1078-0432.CCR-07-1591. Clin Cancer Res. 2007. PMID: 18006756

5

A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas.

Lee TL, Yeh J, Friedman J, Yan B, Yang X, Yeh NT, Van Waes C, Chen Z. Lee TL, et al. Among authors: yang x. Int J Cancer. 2008 May 1;122(9):1987-98. doi: 10.1002/ijc.23324. Int J Cancer. 2008. PMID: 18172861 Free article.

6

ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation.

Yang X, Lu H, Yan B, Romano RA, Bian Y, Friedman J, Duggal P, Allen C, Chuang R, Ehsanian R, Si H, Sinha S, Van Waes C, Chen Z. Yang X, et al. Cancer Res. 2011 May 15;71(10):3688-700. doi: 10.1158/0008-5472.CAN-10-3445. Cancer Res. 2011. PMID: 21576089 Free PMC article.

7

TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer.

Lu H, Yang X, Duggal P, Allen CT, Yan B, Cohen J, Nottingham L, Romano RA, Sinha S, King KE, Weinberg WC, Chen Z, Van Waes C. Lu H, et al. Among authors: yang x. Cancer Res. 2011 Nov 1;71(21):6867-77. doi: 10.1158/0008-5472.CAN-11-2460. Epub 2011 Sep 20. Cancer Res. 2011. PMID: 21933882 Free PMC article.

8

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers.

Freudlsperger C, Bian Y, Contag Wise S, Burnett J, Coupar J, Yang X, Chen Z, Van Waes C. Freudlsperger C, et al. Among authors: yang x. Oncogene. 2013 Mar 21;32(12):1549-59. doi: 10.1038/onc.2012.171. Epub 2012 May 28. Oncogene. 2013. PMID: 22641218 Free PMC article.

9

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.

Nottingham LK, Yan CH, Yang X, Si H, Coupar J, Bian Y, Cheng TF, Allen C, Arun P, Gius D, Dang L, Van Waes C, Chen Z. Nottingham LK, et al. Among authors: yang x. Oncogene. 2014 Feb 27;33(9):1135-47. doi: 10.1038/onc.2013.49. Epub 2013 Mar 4. Oncogene. 2014. PMID: 23455325 Free PMC article.

10

Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers.

Zhang J, Chen T, Yang X, Cheng H, Späth SS, Clavijo PE, Chen J, Silvin C, Issaeva N, Su X, Yarbrough WG, Annunziata CM, Chen Z, Van Waes C. Zhang J, et al. Among authors: yang x. Cancer Res. 2018 Aug 15;78(16):4613-4626. doi: 10.1158/0008-5472.CAN-17-0642. Epub 2018 Jun 19. Cancer Res. 2018. PMID: 29921694 Free PMC article.

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