Bouhaddou M - Search Results

1

A scalable, open-source implementation of a large-scale mechanistic model for single cell proliferation and death signaling.

Erdem C, Mutsuddy A, Bensman EM, Dodd WB, Saint-Antoine MM, Bouhaddou M, Blake RC, Gross SM, Heiser LM, Feltus FA, Birtwistle MR. Erdem C, et al. Among authors: bouhaddou m. Nat Commun. 2022 Jun 21;13(1):3555. doi: 10.1038/s41467-022-31138-1. Nat Commun. 2022. PMID: 35729113 Free PMC article.

2

Dimerization-based control of cooperativity.

Bouhaddou M, Birtwistle MR. Bouhaddou M, et al. Mol Biosyst. 2014 Jul;10(7):1824-32. doi: 10.1039/c4mb00022f. Mol Biosyst. 2014. PMID: 24736836 Free PMC article.

3

Drug response consistency in CCLE and CGP.

Bouhaddou M, DiStefano MS, Riesel EA, Carrasco E, Holzapfel HY, Jones DC, Smith GR, Stern AD, Somani SS, Thompson TV, Birtwistle MR. Bouhaddou M, et al. Nature. 2016 Nov 30;540(7631):E9-E10. doi: 10.1038/nature20580. Nature. 2016. PMID: 27905419 Free PMC article. No abstract available.

4

Integrating Transcriptomic Data with Mechanistic Systems Pharmacology Models for Virtual Drug Combination Trials.

Barrette AM, Bouhaddou M, Birtwistle MR. Barrette AM, et al. Among authors: bouhaddou m. ACS Chem Neurosci. 2018 Jan 17;9(1):118-129. doi: 10.1021/acschemneuro.7b00197. Epub 2017 Oct 6. ACS Chem Neurosci. 2018. PMID: 28950062 Free PMC article.

5

A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries.

Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, Jayaraman G, Lim R, Bouhaddou M, Ornelas L, Bochicchio J, Lenaeus L, Stocksdale J, Shim J, Gomez E, Sareen D, Svendsen C, Thompson LM, Mahajan M, Iyengar R, Sobie EA, Azeloglu EU, Birtwistle MR. Xiong Y, et al. Among authors: bouhaddou m. Sci Rep. 2017 Nov 7;7(1):14626. doi: 10.1038/s41598-017-14892-x. Sci Rep. 2017. PMID: 29116112 Free PMC article.

6

Analysis of copy number loss of the ErbB4 receptor tyrosine kinase in glioblastoma.

Jones DC, Scanteianu A, DiStefano M, Bouhaddou M, Birtwistle MR. Jones DC, et al. Among authors: bouhaddou m. PLoS One. 2018 Jan 17;13(1):e0190664. doi: 10.1371/journal.pone.0190664. eCollection 2018. PLoS One. 2018. PMID: 29342193 Free PMC article.

7

A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens.

Bouhaddou M, Barrette AM, Stern AD, Koch RJ, DiStefano MS, Riesel EA, Santos LC, Tan AL, Mertz AE, Birtwistle MR. Bouhaddou M, et al. PLoS Comput Biol. 2018 Mar 26;14(3):e1005985. doi: 10.1371/journal.pcbi.1005985. eCollection 2018 Mar. PLoS Comput Biol. 2018. PMID: 29579036 Free PMC article.

8

Validating Antibodies for Quantitative Western Blot Measurements with Microwestern Array.

Koch RJ, Barrette AM, Stern AD, Hu B, Bouhaddou M, Azeloglu EU, Iyengar R, Birtwistle MR. Koch RJ, et al. Among authors: bouhaddou m. Sci Rep. 2018 Jul 27;8(1):11329. doi: 10.1038/s41598-018-29436-0. Sci Rep. 2018. PMID: 30054510 Free PMC article.

9

Fluorescence Multiplexing with Spectral Imaging and Combinatorics.

Holzapfel HY, Stern AD, Bouhaddou M, Anglin CM, Putur D, Comer S, Birtwistle MR. Holzapfel HY, et al. Among authors: bouhaddou m. ACS Comb Sci. 2018 Nov 12;20(11):653-659. doi: 10.1021/acscombsci.8b00101. Epub 2018 Oct 30. ACS Comb Sci. 2018. PMID: 30339749 Free PMC article.

10

Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer.

Bouhaddou M, Yu LJ, Lunardi S, Stamatelos SK, Mack F, Gallo JM, Birtwistle MR, Walz AC. Bouhaddou M, et al. Clin Transl Sci. 2020 Mar;13(2):419-429. doi: 10.1111/cts.12727. Epub 2020 Jan 16. Clin Transl Sci. 2020. PMID: 31729169 Free PMC article.

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