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Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.
Varkaris A, Fece de la Cruz F, Martin EE, Norden BL, Chevalier N, Kehlmann AM, Leshchiner I, Barnes H, Ehnstrom S, Stavridi AM, Yuan X, Kim JS, Ellis H, Papatheodoridi A, Gunaydin H, Danysh BP, Parida L, Sanidas I, Ji Y, Lau K, Wulf GM, Bardia A, Spring LM, Isakoff SJ, Lennerz JK, Del Vecchio K, Pierce L, Pazolli E, Getz G, Corcoran RB, Juric D. Varkaris A, et al. Among authors: barnes h. Cancer Discov. 2024 Feb 8;14(2):227-239. doi: 10.1158/2159-8290.CD-23-0704. Cancer Discov. 2024. PMID: 37916958 Free PMC article.
Expression of mitochondrial oxidative stress response genes in muscle is associated with mitochondrial respiration, physical performance, and muscle mass in the Study of Muscle, Mobility, and Aging.
Tranah GJ, Barnes HN, Cawthon PM, Coen PM, Esser KA, Hepple RT, Huo Z, Kramer PA, Toledo FGS, Zhang X, Wu K, Wolff CA, Evans DS, Cummings SR. Tranah GJ, et al. Among authors: barnes hn. Aging Cell. 2024 Jun 3:e14114. doi: 10.1111/acel.14114. Online ahead of print. Aging Cell. 2024. PMID: 38831629
Higher expression of denervation-responsive genes is negatively associated with muscle volume and performance traits in the study of muscle, mobility, and aging (SOMMA).
Lukasiewicz CJ, Tranah GJ, Evans DS, Coen PM, Barnes HN, Huo Z, Esser KA, Zhang X, Wolff C, Wu K, Lane NE, Kritchevsky SB, Newman AB, Cummings SR, Cawthon PM, Hepple RT. Lukasiewicz CJ, et al. Among authors: barnes hn. Aging Cell. 2024 Jun 3:e14115. doi: 10.1111/acel.14115. Online ahead of print. Aging Cell. 2024. PMID: 38831622
Measurement and Incorporation of Laryngeal Motion Using cine-MRI on an MR-Linear Accelerator to Generate Radiation Therapy Plans for Early-stage Squamous Cell Cancers of the Glottis.
Gupta A, McQuaid D, Dunlop A, Barnes H, Mohajer J, Smith G, Nartey J, Morrison K, Herbert T, Alexander S, McNair H, Newbold K, Nutting C, Bhide S, Harrington KJ, Wong KH. Gupta A, et al. Among authors: barnes h. Adv Radiat Oncol. 2024 Mar 12;9(6):101490. doi: 10.1016/j.adro.2024.101490. eCollection 2024 Jun. Adv Radiat Oncol. 2024. PMID: 38681895 Free PMC article.
526 results