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Dynamic rewiring of biological activity across genotype and lineage revealed by context-dependent functional interactions.
Genome Biol. 2022 Jun 29;23(1):140. doi: 10.1186/s13059-022-02712-z.
Genome Biol. 2022.
PMID: 35768873
Free PMC article.
Identifying chemogenetic interactions from CRISPR screens with drugZ.
Colic M, Wang G, Zimmermann M, Mascall K, McLaughlin M, Bertolet L, Lenoir WF, Moffat J, Angers S, Durocher D, Hart T.
Colic M, et al.
Genome Med. 2019 Aug 22;11(1):52. doi: 10.1186/s13073-019-0665-3.
Genome Med. 2019.
PMID: 31439014
Free PMC article.
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Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells.
Lenoir WF, Morgado M, DeWeirdt PC, McLaughlin M, Griffith AL, Sangree AK, Feeley MN, Esmaeili Anvar N, Kim E, Bertolet LL, Colic M, Dede M, Doench JG, Hart T.
Lenoir WF, et al. Among authors: bertolet ll.
Nat Commun. 2021 Nov 11;12(1):6506. doi: 10.1038/s41467-021-26867-8.
Nat Commun. 2021.
PMID: 34764293
Free PMC article.
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AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase.
Yoshihama Y, LaBella KA, Kim E, Bertolet L, Colic M, Li J, Shang X, Wu CJ, Spring DJ, Wang YA, Hart T, DePinho RA.
Yoshihama Y, et al.
Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2026324118. doi: 10.1073/pnas.2026324118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34475205
Free PMC article.
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