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Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer's disease mouse model.
Freitag K, Sterczyk N, Wendlinger S, Obermayer B, Schulz J, Farztdinov V, Mülleder M, Ralser M, Houtman J, Fleck L, Braeuning C, Sansevrino R, Hoffmann C, Milovanovic D, Sigrist SJ, Conrad T, Beule D, Heppner FL, Jendrach M. Freitag K, et al. Among authors: jendrach m. J Neuroinflammation. 2022 Jul 2;19(1):172. doi: 10.1186/s12974-022-02534-7. J Neuroinflammation. 2022. PMID: 35780157 Free PMC article.
CNS myeloid cells critically regulate heat hyperalgesia.
Kälin S, Miller KR, Kälin RE, Jendrach M, Witzel C, Heppner FL. Kälin S, et al. Among authors: jendrach m. J Clin Invest. 2018 Jul 2;128(7):2774-2786. doi: 10.1172/JCI95305. Epub 2018 May 21. J Clin Invest. 2018. PMID: 29634489 Free PMC article.
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.
Leuner K, Schütt T, Kurz C, Eckert SH, Schiller C, Occhipinti A, Mai S, Jendrach M, Eckert GP, Kruse SE, Palmiter RD, Brandt U, Dröse S, Wittig I, Willem M, Haass C, Reichert AS, Müller WE. Leuner K, et al. Among authors: jendrach m. Antioxid Redox Signal. 2012 Jun 15;16(12):1421-33. doi: 10.1089/ars.2011.4173. Epub 2012 Feb 28. Antioxid Redox Signal. 2012. PMID: 22229260 Free PMC article.
A new link to mitochondrial impairment in tauopathies.
Schulz KL, Eckert A, Rhein V, Mai S, Haase W, Reichert AS, Jendrach M, Müller WE, Leuner K. Schulz KL, et al. Among authors: jendrach m. Mol Neurobiol. 2012 Aug;46(1):205-16. doi: 10.1007/s12035-012-8308-3. Epub 2012 Jul 31. Mol Neurobiol. 2012. PMID: 22847631
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.
Gispert S, Ricciardi F, Kurz A, Azizov M, Hoepken HH, Becker D, Voos W, Leuner K, Müller WE, Kudin AP, Kunz WS, Zimmermann A, Roeper J, Wenzel D, Jendrach M, García-Arencíbia M, Fernández-Ruiz J, Huber L, Rohrer H, Barrera M, Reichert AS, Rüb U, Chen A, Nussbaum RL, Auburger G. Gispert S, et al. Among authors: jendrach m. PLoS One. 2009 Jun 3;4(6):e5777. doi: 10.1371/journal.pone.0005777. PLoS One. 2009. PMID: 19492057 Free PMC article.
Do UCP2 and mild uncoupling improve longevity?
Dikov D, Aulbach A, Muster B, Dröse S, Jendrach M, Bereiter-Hahn J. Dikov D, et al. Among authors: jendrach m. Exp Gerontol. 2010 Aug;45(7-8):586-95. doi: 10.1016/j.exger.2010.03.011. Epub 2010 Mar 21. Exp Gerontol. 2010. PMID: 20332018
Primary skin fibroblasts as a model of Parkinson's disease.
Auburger G, Klinkenberg M, Drost J, Marcus K, Morales-Gordo B, Kunz WS, Brandt U, Broccoli V, Reichmann H, Gispert S, Jendrach M. Auburger G, et al. Among authors: jendrach m. Mol Neurobiol. 2012 Aug;46(1):20-7. doi: 10.1007/s12035-012-8245-1. Epub 2012 Feb 19. Mol Neurobiol. 2012. PMID: 22350618 Free PMC article. Review.
Loss of PINK1 impairs stress-induced autophagy and cell survival.
Parganlija D, Klinkenberg M, Domínguez-Bautista J, Hetzel M, Gispert S, Chimi MA, Dröse S, Mai S, Brandt U, Auburger G, Jendrach M. Parganlija D, et al. Among authors: jendrach m. PLoS One. 2014 Apr 21;9(4):e95288. doi: 10.1371/journal.pone.0095288. eCollection 2014. PLoS One. 2014. PMID: 24751806 Free PMC article.
41 results