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Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery.
Mol Cell. 2022 Aug 18;82(16):2939-2951.e5. doi: 10.1016/j.molcel.2022.06.011. Epub 2022 Jul 5.
Mol Cell. 2022.
PMID: 35793673
Free PMC article.
Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo.
Shao Z, Lee BJ, Rouleau-Turcotte É, Langelier MF, Lin X, Estes VM, Pascal JM, Zha S.
Shao Z, et al. Among authors: rouleau turcotte e.
Nucleic Acids Res. 2020 Sep 25;48(17):9694-9709. doi: 10.1093/nar/gkaa718.
Nucleic Acids Res. 2020.
PMID: 32890402
Free PMC article.
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Bridging a DNA Break to Leave a Poly(ADP-Ribose) Mark on Chromatin.
Rouleau-Turcotte É, Pascal JM.
Rouleau-Turcotte É, et al.
Mol Cell. 2020 Nov 19;80(4):560-561. doi: 10.1016/j.molcel.2020.10.044.
Mol Cell. 2020.
PMID: 33217315
Free article.
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ADP-ribose contributions to genome stability and PARP enzyme trapping on sites of DNA damage; paradigm shifts for a coming-of-age modification.
Rouleau-Turcotte É, Pascal JM.
Rouleau-Turcotte É, et al.
J Biol Chem. 2023 Dec;299(12):105397. doi: 10.1016/j.jbc.2023.105397. Epub 2023 Oct 28.
J Biol Chem. 2023.
PMID: 37898399
Free PMC article.
Review.
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Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.
Velagapudi UK, Rouleau-Turcotte É, Billur R, Shao X, Patil M, Black BE, Pascal JM, Talele TT.
Velagapudi UK, et al. Among authors: rouleau turcotte e.
Biochem J. 2024 Mar 20;481(6):437-460. doi: 10.1042/BCJ20230406.
Biochem J. 2024.
PMID: 38372302
Free PMC article.
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