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Nogo-A reduces ceramide de novo biosynthesis to protect from heart failure.
Cardiovasc Res. 2023 Mar 31;119(2):506-519. doi: 10.1093/cvr/cvac108.
Cardiovasc Res. 2023.
PMID: 35815623
Free PMC article.
Pressure overload leads to coronary plaque formation, progression, and myocardial events in ApoE-/- mice.
Marino A, Zhang Y, Rubinelli L, Riemma MA, Ip JE, Di Lorenzo A.
Marino A, et al. Among authors: rubinelli l.
JCI Insight. 2019 May 2;4(9):e128220. doi: 10.1172/jci.insight.128220. eCollection 2019 May 2.
JCI Insight. 2019.
PMID: 31045580
Free PMC article.
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Endothelial Sphingolipid De Novo Synthesis Controls Blood Pressure by Regulating Signal Transduction and NO via Ceramide.
Cantalupo A, Sasset L, Gargiulo A, Rubinelli L, Del Gaudio I, Benvenuto D, Wadsack C, Jiang XC, Bucci MR, Di Lorenzo A.
Cantalupo A, et al. Among authors: rubinelli l.
Hypertension. 2020 May;75(5):1279-1288. doi: 10.1161/HYPERTENSIONAHA.119.14507. Epub 2020 Mar 16.
Hypertension. 2020.
PMID: 32172624
Free PMC article.
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Endothelial Spns2 and ApoM Regulation of Vascular Tone and Hypertension Via Sphingosine-1-Phosphate.
Del Gaudio I, Rubinelli L, Sasset L, Wadsack C, Hla T, Di Lorenzo A.
Del Gaudio I, et al. Among authors: rubinelli l.
J Am Heart Assoc. 2021 Jul 20;10(14):e021261. doi: 10.1161/JAHA.121.021261. Epub 2021 Jul 9.
J Am Heart Assoc. 2021.
PMID: 34240614
Free PMC article.
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Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over Ceramide Protects From Coronary Atherosclerosis.
Manzo OL, Nour J, Sasset L, Marino A, Rubinelli L, Palikhe S, Smimmo M, Hu Y, Bucci MR, Borczuk A, Elemento O, Freed JK, Norata GD, Di Lorenzo A.
Manzo OL, et al. Among authors: rubinelli l.
Circ Res. 2024 Apr 12;134(8):990-1005. doi: 10.1161/CIRCRESAHA.123.323826. Epub 2024 Mar 8.
Circ Res. 2024.
PMID: 38456287
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Essential Role of Endothelial Sphingolipid Biosynthesis in Cerebrovascular Homeostasis.
Rubinelli L, Garcia-Bonilla L, Sasset L, Cantalupo A, Goya B, Ip JE, Anrather J, Iadecola C, Faraco G, Di Lorenzo A.
Rubinelli L, et al.
Circ Res. 2023 Oct 27;133(10):880-882. doi: 10.1161/CIRCRESAHA.123.323183. Epub 2023 Oct 4.
Circ Res. 2023.
PMID: 37791485
No abstract available.
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Sphingosine-1-phosphate controls endothelial sphingolipid homeostasis via ORMDL.
Sasset L, Chowdhury KH, Manzo OL, Rubinelli L, Konrad C, Maschek JA, Manfredi G, Holland WL, Di Lorenzo A.
Sasset L, et al. Among authors: rubinelli l.
EMBO Rep. 2023 Jan 9;24(1):e54689. doi: 10.15252/embr.202254689. Epub 2022 Nov 21.
EMBO Rep. 2023.
PMID: 36408842
Free PMC article.
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