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Dupilumab significantly improves skin barrier function in patients with moderate-to-severe atopic dermatitis.
Berdyshev E, Goleva E, Bissonnette R, Bronova I, Bronoff AS, Richers BN, Garcia S, Ramirez-Gama M, Taylor P, Praestgaard A, Agueusop I, Jurvilliers P, Boguniewicz M, Levit NA, Rossi AB, Zhang A, Leung DYM. Berdyshev E, et al. Among authors: richers bn. Allergy. 2022 Nov;77(11):3388-3397. doi: 10.1111/all.15432. Epub 2022 Jul 21. Allergy. 2022. PMID: 35815904
Minimally invasive skin tape strip RNA sequencing identifies novel characteristics of the type 2-high atopic dermatitis disease endotype.
Dyjack N, Goleva E, Rios C, Kim BE, Bin L, Taylor P, Bronchick C, Hall CF, Richers BN, Seibold MA, Leung DYM. Dyjack N, et al. Among authors: richers bn. J Allergy Clin Immunol. 2018 Apr;141(4):1298-1309. doi: 10.1016/j.jaci.2017.10.046. Epub 2018 Jan 6. J Allergy Clin Immunol. 2018. PMID: 29309794 Free PMC article. Clinical Trial.
Lipid abnormalities in atopic skin are driven by type 2 cytokines.
Berdyshev E, Goleva E, Bronova I, Dyjack N, Rios C, Jung J, Taylor P, Jeong M, Hall CF, Richers BN, Norquest KA, Zheng T, Seibold MA, Leung DY. Berdyshev E, et al. Among authors: richers bn. JCI Insight. 2018 Feb 22;3(4):e98006. doi: 10.1172/jci.insight.98006. eCollection 2018 Feb 22. JCI Insight. 2018. PMID: 29467325 Free PMC article. Clinical Trial.
The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype.
Leung DYM, Calatroni A, Zaramela LS, LeBeau PK, Dyjack N, Brar K, David G, Johnson K, Leung S, Ramirez-Gama M, Liang B, Rios C, Montgomery MT, Richers BN, Hall CF, Norquest KA, Jung J, Bronova I, Kreimer S, Talbot CC Jr, Crumrine D, Cole RN, Elias P, Zengler K, Seibold MA, Berdyshev E, Goleva E. Leung DYM, et al. Among authors: richers bn. Sci Transl Med. 2019 Feb 20;11(480):eaav2685. doi: 10.1126/scitranslmed.aav2685. Sci Transl Med. 2019. PMID: 30787169 Free PMC article.
16 results