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Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains.
Chen C, Saville JW, Marti MM, Schäfer A, Cheng MH, Mannar D, Zhu X, Berezuk AM, Banerjee A, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Enick N, McCormick KD, Liu X, Adams C, Hines MG, Sun Z, Chen W, Jacobs JL, Barratt-Boyes SM, Mellors JW, Baric RS, Bahar I, Dimitrov DS, Subramaniam S, Martinez DR, Li W. Chen C, et al. Among authors: barratt boyes sm. iScience. 2022 Aug 19;25(8):104798. doi: 10.1016/j.isci.2022.104798. Epub 2022 Jul 20. iScience. 2022. PMID: 35875685 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With Coronavirus Disease 2019 Severity and Predicts Clinical Outcomes.
Jacobs JL, Bain W, Naqvi A, Staines B, Castanha PMS, Yang H, Boltz VF, Barratt-Boyes S, Marques ETA, Mitchell SL, Methé B, Olonisakin TF, Haidar G, Burke TW, Petzold E, Denny T, Woods CW, McVerry BJ, Lee JS, Watkins SC, St Croix CM, Morris A, Kearney MF, Ladinsky MS, Bjorkman PJ, Kitsios GD, Mellors JW. Jacobs JL, et al. Clin Infect Dis. 2022 May 3;74(9):1525-1533. doi: 10.1093/cid/ciab686. Clin Infect Dis. 2022. PMID: 34374761 Free PMC article.
Contribution of Coronavirus-Specific Immunoglobulin G Responses to Complement Overactivation in Patients with Severe Coronavirus Disease 2019.
Castanha PMS, Tuttle DJ, Kitsios GD, Jacobs JL, Braga-Neto U, Duespohl M, Rathod S, Marti MM, Wheeler S, Naqvi A, Staines B, Mellors J, Morris A, McVerry BJ, Shah F, Schaefer C, Macatangay BJC, Methe B, Fernandez CA, Barratt-Boyes SM, Burke D, Marques ETA. Castanha PMS, et al. Among authors: barratt boyes sm. J Infect Dis. 2022 Sep 13;226(5):766-777. doi: 10.1093/infdis/jiac091. J Infect Dis. 2022. PMID: 35267024 Free PMC article.
Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates.
Corry J, Kettenburg G, Upadhyay AA, Wallace M, Marti MM, Wonderlich ER, Bissel SJ, Goss K, Sturgeon TJ, Watkins SC, Reed DS, Bosinger SE, Barratt-Boyes SM. Corry J, et al. Among authors: barratt boyes sm. PLoS Pathog. 2022 Mar 10;18(3):e1010395. doi: 10.1371/journal.ppat.1010395. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35271686 Free PMC article.
SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.
Mannar D, Saville JW, Sun Z, Zhu X, Marti MM, Srivastava SS, Berezuk AM, Zhou S, Tuttle KS, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Jacobs JL, Barratt-Boyes SM, Mellors JW, Dimitrov DS, Li W, Subramaniam S. Mannar D, et al. Among authors: barratt boyes sm. Nat Commun. 2022 Aug 18;13(1):4696. doi: 10.1038/s41467-022-32262-8. Nat Commun. 2022. PMID: 35982054 Free PMC article.
Rapid Emergence of Potentially Transmissible Severe Acute Respiratory Syndrome Coronavirus 2 With Resistance to Combination Monoclonal Antibody Therapy.
Jacobs JL, Haidar G, Naqvi A, McCormick KD, Sobolewski M, Treat BR, Heaps AL, Simpson J, Kramer KH, McCreary E, Bariola JR, Klamar-Blain C, Macatangay BJC, Dimitrov D, Li W, Marino CC, Raptis A, Sethi R, Chandran U, Barratt-Boyes S, Parikh UM, Mellors JW. Jacobs JL, et al. Open Forum Infect Dis. 2023 May 17;10(5):ofad278. doi: 10.1093/ofid/ofad278. eCollection 2023 May. Open Forum Infect Dis. 2023. PMID: 37265667 Free PMC article.
Refined semi-lethal aerosol H5N1 influenza model in cynomolgus macaques for evaluation of medical countermeasures.
Kanekiyo M, Gillespie RA, Midgett M, O'Malley KJ, Williams C, Moin SM, Wallace M, Treaster L, Cooper K, Syeda H, Kettenburg G, Rannulu H, Schmer T, Ortiz L, Da Silva Castanha P, Corry J, Xia M, Olsen E, Perez D, Yun G, Graham BS, Barratt-Boyes SM, Reed DS. Kanekiyo M, et al. Among authors: barratt boyes sm. iScience. 2023 Sep 6;26(10):107830. doi: 10.1016/j.isci.2023.107830. eCollection 2023 Oct 20. iScience. 2023. PMID: 37766976 Free PMC article.
SARS-CoV-2 mRNA Vaccines Induce Greater Complement Activation and Decreased Viremia and Nef Antibodies in Men With HIV-1.
Tuttle DJ, Castanha PMS, Nasser A, Wilkins MS, Galarza TG, Alaoui-El-Azher M, Cuff DE, Chhibbar P, Das J, Li Y, Barratt-Boyes SM, Mailliard RB, Sluis-Cremer N, Rinaldo CR, Marques ETA. Tuttle DJ, et al. Among authors: barratt boyes sm. J Infect Dis. 2024 Apr 12;229(4):1147-1157. doi: 10.1093/infdis/jiad544. J Infect Dis. 2024. PMID: 38035792
Effects of a SARS-associated coronavirus vaccine in monkeys.
Gao W, Tamin A, Soloff A, D'Aiuto L, Nwanegbo E, Robbins PD, Bellini WJ, Barratt-Boyes S, Gambotto A. Gao W, et al. Lancet. 2003 Dec 6;362(9399):1895-6. doi: 10.1016/S0140-6736(03)14962-8. Lancet. 2003. PMID: 14667748 Free PMC article.
76 results