Li W - Search Results

1

Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains.

Chen C, Saville JW, Marti MM, Schäfer A, Cheng MH, Mannar D, Zhu X, Berezuk AM, Banerjee A, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Enick N, McCormick KD, Liu X, Adams C, Hines MG, Sun Z, Chen W, Jacobs JL, Barratt-Boyes SM, Mellors JW, Baric RS, Bahar I, Dimitrov DS, Subramaniam S, Martinez DR, Li W. Chen C, et al. Among authors: li w. iScience. 2022 Aug 19;25(8):104798. doi: 10.1016/j.isci.2022.104798. Epub 2022 Jul 20. iScience. 2022. PMID: 35875685 Free PMC article.

2

Germlining of the HIV-1 broadly neutralizing antibody domain m36.

Chen W, Li W, Ying T, Wang Y, Feng Y, Dimitrov DS. Chen W, et al. Among authors: li w. Antiviral Res. 2015 Apr;116:62-6. doi: 10.1016/j.antiviral.2015.02.001. Epub 2015 Feb 9. Antiviral Res. 2015. PMID: 25676867 Free PMC article.

3

Discovery of T-Cell Infection and Apoptosis by Middle East Respiratory Syndrome Coronavirus.

Ying T, Li W, Dimitrov DS. Ying T, et al. Among authors: li w. J Infect Dis. 2016 Mar 15;213(6):877-9. doi: 10.1093/infdis/jiv381. Epub 2015 Jul 22. J Infect Dis. 2016. PMID: 26203059 Free PMC article. No abstract available.

4

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody.

Ying T, Prabakaran P, Du L, Shi W, Feng Y, Wang Y, Wang L, Li W, Jiang S, Dimitrov DS, Zhou T. Ying T, et al. Among authors: li w. Nat Commun. 2015 Sep 15;6:8223. doi: 10.1038/ncomms9223. Nat Commun. 2015. PMID: 26370782 Free PMC article.

5

Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1.

Chen W, Bardhi A, Feng Y, Wang Y, Qi Q, Li W, Zhu Z, Dyba MA, Ying T, Jiang S, Goldstein H, Dimitrov DS. Chen W, et al. Among authors: li w. MAbs. 2016 May-Jun;8(4):761-74. doi: 10.1080/19420862.2016.1160180. Epub 2016 Mar 10. MAbs. 2016. PMID: 26963639 Free PMC article.

6

Identification of high-affinity anti-CD16A allotype-independent human antibody domains.

Li W, Yang H, Dimitrov DS. Li W, et al. Exp Mol Pathol. 2016 Oct;101(2):281-289. doi: 10.1016/j.yexmp.2016.10.001. Epub 2016 Oct 3. Exp Mol Pathol. 2016. PMID: 27712994 Free PMC article.

7

One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells.

Li W, Wu Y, Kong D, Yang H, Wang Y, Shao J, Feng Y, Chen W, Ma L, Ying T, Dimitrov DS. Li W, et al. Sci Rep. 2017 Aug 22;7(1):9130. doi: 10.1038/s41598-017-07966-3. Sci Rep. 2017. PMID: 28831040 Free PMC article.

8

Crystallizable Fragment Glycoengineering for Therapeutic Antibodies Development.

Li W, Zhu Z, Chen W, Feng Y, Dimitrov DS. Li W, et al. Front Immunol. 2017 Nov 13;8:1554. doi: 10.3389/fimmu.2017.01554. eCollection 2017. Front Immunol. 2017. PMID: 29181010 Free PMC article. Review.

9

A defucosylated bispecific multivalent molecule exhibits broad HIV-1-neutralizing activity and enhanced antibody-dependent cellular cytotoxicity against reactivated HIV-1 latently infected cells.

Kong D, Wang Y, Ji P, Li W, Ying T, Huang J, Wang C, Wu Y, Wang Y, Chen W, Hao Y, Hong K, Shao Y, Dimitrov DS, Jiang S, Ma L. Kong D, et al. Among authors: li w. AIDS. 2018 Aug 24;32(13):1749-1761. doi: 10.1097/QAD.0000000000001869. AIDS. 2018. PMID: 29762173

10

Optimization of the C-Terminus of an Autonomous Human IgG1 CH2 Domain for Stability and Aggregation Resistance.

Gao X, Conard A, Yang C, Zhan Y, Zeng F, Shi J, Li W, Dimitrov DS, Gong R. Gao X, et al. Among authors: li w. Mol Pharm. 2019 Aug 5;16(8):3647-3656. doi: 10.1021/acs.molpharmaceut.9b00544. Epub 2019 Jul 22. Mol Pharm. 2019. PMID: 31282682

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