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High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults.
Roider J, Maehara T, Ngoepe A, Ramsuran D, Muenchhoff M, Adland E, Aicher T, Kazer SW, Jooste P, Karim F, Kuhn W, Shalek AK, Ndung'u T, Morris L, Moore PL, Pillai S, Kløverpris H, Goulder P, Leslie A. Roider J, et al. Among authors: karim f. Front Immunol. 2018 Sep 12;9:1975. doi: 10.3389/fimmu.2018.01975. eCollection 2018. Front Immunol. 2018. PMID: 30258437 Free PMC article. Clinical Trial.
Contrasting Inflammatory Signatures in Peripheral Blood and Bronchoalveolar Cells Reveal Compartment-Specific Effects of HIV Infection.
Muema DM, Mthembu M, Schiff AE, Singh U, Corleis B, Chen D, Bassett T, Rasehlo SS, Nyamande K, Khan DF, Maharaj P, Mitha M, Suleman M, Mhlane Z, Naidoo T, Ramjit D, Karim F, Kwon DS, Ndung'u T, Wong EB. Muema DM, et al. Among authors: karim f. Front Immunol. 2020 May 19;11:864. doi: 10.3389/fimmu.2020.00864. eCollection 2020. Front Immunol. 2020. PMID: 32508817 Free PMC article.
Increased Neutrophil Count and Decreased Neutrophil CD15 Expression Correlate With TB Disease Severity and Treatment Response Irrespective of HIV Co-infection.
Ndlovu LN, Peetluk L, Moodley S, Nhamoyebonde S, Ngoepe AT, Mazibuko M, Khan K, Karim F, Pym AS, Maruri F, Moosa MS, van der Heijden YF, Sterling TR, Leslie A. Ndlovu LN, et al. Among authors: karim f. Front Immunol. 2020 Aug 28;11:1872. doi: 10.3389/fimmu.2020.01872. eCollection 2020. Front Immunol. 2020. PMID: 32983107 Free PMC article.
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma.
Cele S, Gazy I, Jackson L, Hwa SH, Tegally H, Lustig G, Giandhari J, Pillay S, Wilkinson E, Naidoo Y, Karim F, Ganga Y, Khan K, Bernstein M, Balazs AB, Gosnell BI, Hanekom W, Moosa MS; Network for Genomic Surveillance in South Africa; COMMIT-KZN Team; Lessells RJ, de Oliveira T, Sigal A. Cele S, et al. Among authors: karim f. Nature. 2021 May;593(7857):142-146. doi: 10.1038/s41586-021-03471-w. Epub 2021 Mar 29. Nature. 2021. PMID: 33780970 Free PMC article.
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells.
Fardoos R, Asowata OE, Herbert N, Nyquist SK, Zungu Y, Singh A, Ngoepe A, Mbano IM, Mthabela N, Ramjit D, Karim F, Kuhn W, Madela FG, Manzini VT, Anderson F, Berger B, Pers TH, Shalek AK, Leslie A, Kløverpris HN. Fardoos R, et al. Among authors: karim f. JCI Insight. 2021 Aug 23;6(16):e148920. doi: 10.1172/jci.insight.148920. JCI Insight. 2021. PMID: 34252054 Free PMC article.
Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and With Human Immunodeficiency Virus on Antiretroviral Therapy During the First South African Infection Wave.
Snyman J, Hwa SH, Krause R, Muema D, Reddy T, Ganga Y, Karim F, Leslie A, Sigal A, Ndung'u T; COVID-19 Mechanisms and Multi-omics at the Intersection of TB and HIV in KwaZulu-Natal (COMMIT-KZN Team). Snyman J, et al. Among authors: karim f. Clin Infect Dis. 2022 Aug 24;75(1):e249-e256. doi: 10.1093/cid/ciab758. Clin Infect Dis. 2022. PMID: 34472583 Free PMC article.
T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy.
Lustig G, Cele S, Karim F, Derache A, Ngoepe A, Khan K, Gosnell BI, Moosa MS, Ntshuba N, Marais S, Jeena PM, Govender K, Adamson J, Kløverpris H, Gupta RK, Harrichandparsad R, Patel VB, Sigal A. Lustig G, et al. Among authors: karim f. PLoS Pathog. 2021 Sep 23;17(9):e1009871. doi: 10.1371/journal.ppat.1009871. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34555123 Free PMC article.
HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave.
Karim F, Gazy I, Cele S, Zungu Y, Krause R, Bernstein M, Khan K, Ganga Y, Rodel H, Mthabela N, Mazibuko M, Muema D, Ramjit D, Ndung'u T, Hanekom W, Gosnell B; COMMIT-KZN Team; Lessells RJ, Wong EB, de Oliveira T, Moosa MS, Lustig G, Leslie A, Kløverpris H, Sigal A. Karim F, et al. Elife. 2021 Oct 5;10:e67397. doi: 10.7554/eLife.67397. Elife. 2021. PMID: 34608862 Free PMC article.
658 results