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411 results

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Targeting ESR1 mutation-induced transcriptional addiction in breast cancer with BET inhibition.
Udden SN, Wang Q, Kumar S, Malladi VS, Wu SY, Wei S, Posner BA, Geboers S, Williams NS, Liu Y, Sharma JK, Mani RS, Malladi S, Parra K, Hofstad M, Raj GV, Larios JM, Jagsi R, Wicha MS, Park BH, Gupta GP, Chinnaiyan AM, Chiang CM, Alluri PG. Udden SN, et al. Among authors: williams ns. JCI Insight. 2022 Sep 8;7(17):e151851. doi: 10.1172/jci.insight.151851. JCI Insight. 2022. PMID: 35881485 Free PMC article.
Targeting QseC signaling and virulence for antibiotic development.
Rasko DA, Moreira CG, Li de R, Reading NC, Ritchie JM, Waldor MK, Williams N, Taussig R, Wei S, Roth M, Hughes DT, Huntley JF, Fina MW, Falck JR, Sperandio V. Rasko DA, et al. Science. 2008 Aug 22;321(5892):1078-80. doi: 10.1126/science.1160354. Science. 2008. PMID: 18719281 Free PMC article.
Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.
Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM. Mata MA, et al. Nat Chem Biol. 2011 Sep 11;7(10):712-9. doi: 10.1038/nchembio.645. Nat Chem Biol. 2011. PMID: 21909097 Free PMC article.
A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma.
Sivanand S, Peña-Llopis S, Zhao H, Kucejova B, Spence P, Pavia-Jimenez A, Yamasaki T, McBride DJ, Gillen J, Wolff NC, Morlock L, Lotan Y, Raj GV, Sagalowsky A, Margulis V, Cadeddu JA, Ross MT, Bentley DR, Kabbani W, Xie XJ, Kapur P, Williams NS, Brugarolas J. Sivanand S, et al. Among authors: williams ns. Sci Transl Med. 2012 Jun 6;4(137):137ra75. doi: 10.1126/scitranslmed.3003643. Sci Transl Med. 2012. PMID: 22674553 Free PMC article.
Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.
Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA. Kim HS, et al. Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24. Cell. 2013. PMID: 24243015 Free PMC article.
TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration.
Zhang Y, Desai A, Yang SY, Bae KB, Antczak MI, Fink SP, Tiwari S, Willis JE, Williams NS, Dawson DM, Wald D, Chen WD, Wang Z, Kasturi L, Larusch GA, He L, Cominelli F, Di Martino L, Djuric Z, Milne GL, Chance M, Sanabria J, Dealwis C, Mikkola D, Naidoo J, Wei S, Tai HH, Gerson SL, Ready JM, Posner B, Willson JK, Markowitz SD. Zhang Y, et al. Among authors: williams ns. Science. 2015 Jun 12;348(6240):aaa2340. doi: 10.1126/science.aaa2340. Science. 2015. PMID: 26068857 Free PMC article.
High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma.
Wolff NC, Pavía-Jiménez A, Tcheuyap VT, Alexander S, Vishwanath M, Christie A, Xie XJ, Williams NS, Kapur P, Posner B, McKay RM, Brugarolas J. Wolff NC, et al. Among authors: williams ns. Oncotarget. 2015 Jul 10;6(19):16951-62. doi: 10.18632/oncotarget.4773. Oncotarget. 2015. PMID: 26219258 Free PMC article.
411 results