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A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions.
Liu Y, Zhang X, Liu J, Xia H, Zou J, Muruato AE, Periasamy S, Kurhade C, Plante JA, Bopp NE, Kalveram B, Bukreyev A, Ren P, Wang T, Menachery VD, Plante KS, Xie X, Weaver SC, Shi PY. Liu Y, et al. Among authors: muruato ae. Nat Commun. 2022 Jul 27;13(1):4337. doi: 10.1038/s41467-022-31930-z. Nat Commun. 2022. PMID: 35896528 Free PMC article.
An Infectious cDNA Clone of SARS-CoV-2.
Xie X, Muruato A, Lokugamage KG, Narayanan K, Zhang X, Zou J, Liu J, Schindewolf C, Bopp NE, Aguilar PV, Plante KS, Weaver SC, Makino S, LeDuc JW, Menachery VD, Shi PY. Xie X, et al. Cell Host Microbe. 2020 May 13;27(5):841-848.e3. doi: 10.1016/j.chom.2020.04.004. Epub 2020 Apr 13. Cell Host Microbe. 2020. PMID: 32289263 Free PMC article.
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Johnson BA, Xie X, Bailey AL, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Winkler ES, Swetnam D, Plante JA, Aguilar P, Plante KS, Popov V, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Diamond MS, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4. Epub 2021 Jan 25. Nature. 2021. PMID: 33494095 Free PMC article.
Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.
Muruato A, Vu MN, Johnson BA, Davis-Gardner ME, Vanderheiden A, Lokugamage K, Schindewolf C, Crocquet-Valdes PA, Langsjoen RM, Plante JA, Plante KS, Weaver SC, Debbink K, Routh AL, Walker D, Suthar MS, Shi PY, Xie X, Menachery VD. Muruato A, et al. PLoS Biol. 2021 Nov 4;19(11):e3001284. doi: 10.1371/journal.pbio.3001284. eCollection 2021 Nov. PLoS Biol. 2021. PMID: 34735434 Free PMC article.
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage.
Shan C, Muruato AE, Jagger BW, Richner J, Nunes BTD, Medeiros DBA, Xie X, Nunes JGC, Morabito KM, Kong WP, Pierson TC, Barrett AD, Weaver SC, Rossi SL, Vasconcelos PFC, Graham BS, Diamond MS, Shi PY. Shan C, et al. Among authors: muruato ae. Nat Commun. 2017 Sep 22;8(1):676. doi: 10.1038/s41467-017-00737-8. Nat Commun. 2017. PMID: 28939807 Free PMC article.
A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission.
Xie X, Kum DB, Xia H, Luo H, Shan C, Zou J, Muruato AE, Medeiros DBA, Nunes BTD, Dallmeier K, Rossi SL, Weaver SC, Neyts J, Wang T, Vasconcelos PFC, Shi PY. Xie X, et al. Among authors: muruato ae. Cell Host Microbe. 2018 Oct 10;24(4):487-499.e5. doi: 10.1016/j.chom.2018.09.008. Cell Host Microbe. 2018. PMID: 30308155 Free PMC article.
Genetic stability of live-attenuated Zika vaccine candidates.
Muruato AE, Shan C, Fontes-Garfias CR, Liu Y, Cao Z, Gao Q, Weaver SC, Shi PY. Muruato AE, et al. Antiviral Res. 2019 Nov;171:104596. doi: 10.1016/j.antiviral.2019.104596. Epub 2019 Sep 4. Antiviral Res. 2019. PMID: 31493417
46 results