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Targeting lipid biosynthesis pathways for hepatitis B virus cure.
Hyrina A, Burdette D, Song Z, Ramirez R, Okesli-Armlovich A, Vijayakumar A, Bates J, Trevaskis JL, Fletcher SP, Lee WA, Holdorf MM. Hyrina A, et al. Among authors: holdorf mm. PLoS One. 2022 Aug 4;17(8):e0270273. doi: 10.1371/journal.pone.0270273. eCollection 2022. PLoS One. 2022. PMID: 35925919 Free PMC article.
Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo.
Gorsuch CL, Nemec P, Yu M, Xu S, Han D, Smith J, Lape J, van Buuren N, Ramirez R, Muench RC, Holdorf MM, Feierbach B, Falls G, Holt J, Shoop W, Sevigny E, Karriker F, Brown RV, Joshi A, Goodwin T, Tam YK, Lin PJC, Semple SC, Leatherbury N, Delaney Iv WE, Jantz D, Rhoden Smith A. Gorsuch CL, et al. Among authors: holdorf mm. Mol Ther. 2022 Sep 7;30(9):2909-2922. doi: 10.1016/j.ymthe.2022.05.013. Epub 2022 May 16. Mol Ther. 2022. PMID: 35581938 Free PMC article.
An OX40/OX40L interaction directs successful immunity to hepatitis B virus.
Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper S, Baron JL. Publicover J, et al. Sci Transl Med. 2018 Mar 21;10(433):eaah5766. doi: 10.1126/scitranslmed.aah5766. Sci Transl Med. 2018. PMID: 29563320 Free PMC article.
15 results