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Page 1
Targeting lipid biosynthesis pathways for hepatitis B virus cure.
Hyrina A, Burdette D, Song Z, Ramirez R, Okesli-Armlovich A, Vijayakumar A, Bates J, Trevaskis JL, Fletcher SP, Lee WA, Holdorf MM. Hyrina A, et al. Among authors: trevaskis jl. PLoS One. 2022 Aug 4;17(8):e0270273. doi: 10.1371/journal.pone.0270273. eCollection 2022. PLoS One. 2022. PMID: 35925919 Free PMC article.
Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis.
Vijayakumar A, Okesli-Armlovich A, Wang T, Olson I, Seung M, Kusam S, Hollenback D, Mahadevan S, Marchand B, Toteva M, Breckenridge DG, Trevaskis JL, Bates J. Vijayakumar A, et al. Among authors: trevaskis jl. Hepatol Commun. 2022 Sep;6(9):2298-2309. doi: 10.1002/hep4.2011. Epub 2022 Jun 23. Hepatol Commun. 2022. PMID: 35735253 Free PMC article.
Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis.
Boland ML, Laker RC, Mather K, Nawrocki A, Oldham S, Boland BB, Lewis H, Conway J, Naylor J, Guionaud S, Feigh M, Veidal SS, Lantier L, McGuinness OP, Grimsby J, Rondinone CM, Jermutus L, Larsen MR, Trevaskis JL, Rhodes CJ. Boland ML, et al. Among authors: trevaskis jl. Nat Metab. 2020 May;2(5):413-431. doi: 10.1038/s42255-020-0209-6. Epub 2020 May 21. Nat Metab. 2020. PMID: 32478287 Free PMC article.
Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli sand rat).
Spolding B, Connor T, Wittmer C, Abreu LL, Kaspi A, Ziemann M, Kaur G, Cooper A, Morrison S, Lee S, Sinclair A, Gibert Y, Trevaskis JL, Roth JD, El-Osta A, Standish R, Walder K. Spolding B, et al. Among authors: trevaskis jl. PLoS One. 2014 Mar 20;9(3):e92656. doi: 10.1371/journal.pone.0092656. eCollection 2014. PLoS One. 2014. PMID: 24651520 Free PMC article.
Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis.
Hansen HH, Ægidius HM, Oró D, Evers SS, Heebøll S, Eriksen PL, Thomsen KL, Bengtsson A, Veidal SS, Feigh M, Suppli MP, Knop FK, Grønbæk H, Miranda D, Trevaskis JL, Vrang N, Jelsing J, Rigbolt KTG. Hansen HH, et al. Among authors: trevaskis jl. BMC Gastroenterol. 2020 Jul 6;20(1):210. doi: 10.1186/s12876-020-01356-2. BMC Gastroenterol. 2020. PMID: 32631250 Free PMC article.
Davalintide (AC2307), a novel amylin-mimetic peptide: enhanced pharmacological properties over native amylin to reduce food intake and body weight.
Mack CM, Soares CJ, Wilson JK, Athanacio JR, Turek VF, Trevaskis JL, Roth JD, Smith PA, Gedulin B, Jodka CM, Roland BL, Adams SH, Lwin A, Herich J, Laugero KD, Vu C, Pittner R, Paterniti JR Jr, Hanley M, Ghosh S, Parkes DG. Mack CM, et al. Among authors: trevaskis jl. Int J Obes (Lond). 2010 Feb;34(2):385-95. doi: 10.1038/ijo.2009.238. Epub 2009 Nov 24. Int J Obes (Lond). 2010. PMID: 19935749
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