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Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type diffuse large B-cell lymphoma.
Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S, van Hoppe S, Burton C, Elshiekh M, Rule S, Crosbie N, Clear A, Calaminici M, Runge H, Hills RK, Scott DW, Rimsza LM, Menon G, Sha C, Davies JR, Nagano A, Davies A, Painter D, Smith A, Gribben J, Naresh KN, Westhead DR, Okosun J, Steele A, Hodson DJ, Balasubramanian S, Johnson P, Wang J, Fitzgibbon J. Bewicke-Copley F, et al. Among authors: steele a. Blood Adv. 2023 Mar 14;7(5):845-855. doi: 10.1182/bloodadvances.2022007536. Blood Adv. 2023. PMID: 35947123 Free PMC article.
B-cell receptor signaling in chronic lymphocytic leukemia.
Stevenson FK, Krysov S, Davies AJ, Steele AJ, Packham G. Stevenson FK, et al. Blood. 2011 Oct 20;118(16):4313-20. doi: 10.1182/blood-2011-06-338855. Epub 2011 Aug 3. Blood. 2011. PMID: 21816833 Free article.
Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK.
Krysov S, Steele AJ, Coelho V, Linley A, Sanchez Hidalgo M, Carter M, Potter KN, Kennedy B, Duncombe AS, Ashton-Key M, Forconi F, Stevenson FK, Packham G. Krysov S, et al. Among authors: steele aj. Blood. 2014 Nov 13;124(20):3101-9. doi: 10.1182/blood-2014-04-567198. Epub 2014 Aug 28. Blood. 2014. PMID: 25170122 Free PMC article.
The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model.
Blunt MD, Carter MJ, Larrayoz M, Smith LD, Aguilar-Hernandez M, Cox KL, Tipton T, Reynolds M, Murphy S, Lemm E, Dias S, Duncombe A, Strefford JC, Johnson PW, Forconi F, Stevenson FK, Packham G, Cragg MS, Steele AJ. Blunt MD, et al. Among authors: steele aj. Blood. 2015 Jun 25;125(26):4032-41. doi: 10.1182/blood-2014-11-610329. Epub 2015 May 8. Blood. 2015. PMID: 25957390 Free article.
IL-4 enhances expression and function of surface IgM in CLL cells.
Aguilar-Hernandez MM, Blunt MD, Dobson R, Yeomans A, Thirdborough S, Larrayoz M, Smith LD, Linley A, Strefford JC, Davies A, Johnson PM, Savelyeva N, Cragg MS, Forconi F, Packham G, Stevenson FK, Steele AJ. Aguilar-Hernandez MM, et al. Among authors: steele aj. Blood. 2016 Jun 16;127(24):3015-25. doi: 10.1182/blood-2015-11-682906. Epub 2016 Mar 21. Blood. 2016. PMID: 27002119 Free article.
Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL.
D'Avola A, Drennan S, Tracy I, Henderson I, Chiecchio L, Larrayoz M, Rose-Zerilli M, Strefford J, Plass C, Johnson PW, Steele AJ, Packham G, Stevenson FK, Oakes CC, Forconi F. D'Avola A, et al. Among authors: steele aj. Blood. 2016 Aug 11;128(6):816-26. doi: 10.1182/blood-2016-03-707786. Epub 2016 Jun 14. Blood. 2016. PMID: 27301861 Free article.
PI3K in CLL: are 2 isoforms better than 1?
Steele AJ. Steele AJ. Blood. 2014 Dec 4;124(24):3508-10. doi: 10.1182/blood-2014-10-605089. Blood. 2014. PMID: 25477481 Free article. No abstract available.
1,116 results