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Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment.
Cancer Immunol Immunother. 2023 Mar;72(3):543-560. doi: 10.1007/s00262-022-03268-4. Epub 2022 Aug 13.
Cancer Immunol Immunother. 2023.
PMID: 35962843
Free PMC article.
Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity.
Fultang L, Booth S, Yogev O, Martins da Costa B, Tubb V, Panetti S, Stavrou V, Scarpa U, Jankevics A, Lloyd G, Southam A, Lee SP, Dunn WB, Chesler L, Mussai F, De Santo C.
Fultang L, et al. Among authors: scarpa u.
Blood. 2020 Sep 3;136(10):1155-1160. doi: 10.1182/blood.2019004500.
Blood. 2020.
PMID: 32573723
Free PMC article.
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MicroRNA Signature of Traumatic Brain Injury: From the Biomarker Discovery to the Point-of-Care.
Di Pietro V, Yakoub KM, Scarpa U, Di Pietro C, Belli A.
Di Pietro V, et al. Among authors: scarpa u.
Front Neurol. 2018 Jun 14;9:429. doi: 10.3389/fneur.2018.00429. eCollection 2018.
Front Neurol. 2018.
PMID: 29963002
Free PMC article.
Review.
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Study of Concussion in Rugby Union through MicroRNAs (SCRUM): a study protocol of a prospective, observational cohort study.
Yakoub KM, O'Halloran P, Davies DJ, Bentley C, Watson CN, Forcione M, Scarpa U, Bishop JRB, Toman E, Hammond D, Cross MJ, Stokes KA, Kemp SPT, Menon DK, Di Pietro V, Belli A.
Yakoub KM, et al. Among authors: scarpa u.
BMJ Open. 2018 Nov 25;8(11):e024245. doi: 10.1136/bmjopen-2018-024245.
BMJ Open. 2018.
PMID: 30478124
Free PMC article.
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PARC: a phase I/II study evaluating the safety and activity of pegylated recombinant human arginase BCT-100 in relapsed/refractory cancers of children and young adults.
Fenwick N, Weston R, Wheatley K, Hodgson J, Marshall L, Elliott M, Makin G, Ng A, Brennan B, Lowis S, Adamski J, Kilday JP, Cox R, Gattens M, Moore A, Trahair T, Ronghe M, Campbell M, Campbell H, Williams MW, Kirby M, Van Eijkelenburg N, Keely J, Scarpa U, Stavrou V, Fultang L, Booth S, Cheng P, De Santo C, Mussai F.
Fenwick N, et al. Among authors: scarpa u.
Front Oncol. 2024 Jan 31;14:1296576. doi: 10.3389/fonc.2024.1296576. eCollection 2024.
Front Oncol. 2024.
PMID: 38357205
Free PMC article.
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Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment.
Panetti S, McJannett N, Fultang L, Booth S, Gneo L, Scarpa U, Smith C, Vardon A, Vettore L, Whalley C, Pan Y, Várnai C, Endou H, Barlow J, Tennant D, Beggs A, Mussai F, De Santo C.
Panetti S, et al. Among authors: scarpa u.
Blood Adv. 2023 May 9;7(9):1754-1761. doi: 10.1182/bloodadvances.2022008272.
Blood Adv. 2023.
PMID: 36521029
Free PMC article.
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A randomised evaluation of low-dose Ara-C plus pegylated recombinant arginase BCT-100 versus low dose Ara-C in older unfit patients with acute myeloid leukaemia: Results from the LI-1 trial.
Mussai F, De Santo C, Cheng P, Thomas IF, Ariti C, Upton L, Scarpa U, Stavrou V, Sydenham M, Burnett AK, Knapper SK, Mehta P, McMullin MF, Copland M, Russell NH, Dennis M.
Mussai F, et al. Among authors: scarpa u.
Br J Haematol. 2023 Mar;200(5):573-578. doi: 10.1111/bjh.18560. Epub 2022 Nov 22.
Br J Haematol. 2023.
PMID: 36413792
Free article.
Clinical Trial.
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