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Page 1
Pure tone audiometry and cerebral pathology in healthy older adults.
Parker T, Cash DM, Lane C, Lu K, Malone IB, Nicholas JM, James S, Keshavan A, Murray-Smith H, Wong A, Buchannan S, Keuss S, Sudre CH, Thomas D, Crutch S, Bamiou DE, Warren JD, Fox NC, Richards M, Schott JM. Parker T, et al. J Neurol Neurosurg Psychiatry. 2020 Feb;91(2):172-176. doi: 10.1136/jnnp-2019-321897. Epub 2019 Nov 7. J Neurol Neurosurg Psychiatry. 2020. PMID: 31699832 Free PMC article.
The epidemiology is promising, but the trial evidence is weak. Why pharmacological dementia risk reduction trials haven't lived up to expectations, and where do we go from here?
Peters R, Dodge HH, James S, Jicha GA, Meyer PF, Richards M, Smith AD, Yassine HN, Abner E, Hainsworth AH, Kehoe PG, Beckett N, Anderson CS, Anstey KJ. Peters R, et al. Alzheimers Dement. 2022 Mar;18(3):507-512. doi: 10.1002/alz.12393. Epub 2021 Nov 2. Alzheimers Dement. 2022. PMID: 34726352
Dementia risk reduction: why haven't the pharmacological risk reduction trials worked? An in-depth exploration of seven established risk factors.
Peters R, Breitner J, James S, Jicha GA, Meyer PF, Richards M, Smith AD, Yassine HN, Abner E, Hainsworth AH, Kehoe PG, Beckett N, Weber C, Anderson C, Anstey KJ, Dodge HH. Peters R, et al. Alzheimers Dement (N Y). 2021 Dec 8;7(1):e12202. doi: 10.1002/trc2.12202. eCollection 2021. Alzheimers Dement (N Y). 2021. PMID: 34934803 Free PMC article. Review.
Peripheral hearing loss at age 70 predicts brain atrophy and associated cognitive change.
Parker TD, Hardy C, Keuss S, Coath W, Cash DM, Lu K, Nicholas JM, James SN, Sudre C, Crutch S, Bamiou DE, Warren JD, Fox NC, Richards M, Schott JM. Parker TD, et al. Among authors: james sn. J Neurol Neurosurg Psychiatry. 2024 Apr 3:jnnp-2023-333101. doi: 10.1136/jnnp-2023-333101. Online ahead of print. J Neurol Neurosurg Psychiatry. 2024. PMID: 38569877 Free article.
Updating the study protocol: Insight 46 - a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development - phases 2 and 3.
Murray-Smith H, Barker S, Barkhof F, Barnes J, Brown TM, Captur G, R E Cartlidge M, Cash DM, Coath W, Davis D, Dickson JC, Groves J, Hughes AD, James SN, Keshavan A, Keuss SE, King-Robson J, Lu K, Malone IB, Nicholas JM, Rapala A, Scott CJ, Street R, Sudre CH, Thomas DL, Wong A, Wray S, Zetterberg H, Chaturvedi N, Fox NC, Crutch SJ, Richards M, Schott JM. Murray-Smith H, et al. Among authors: james sn. BMC Neurol. 2024 Jan 23;24(1):40. doi: 10.1186/s12883-023-03465-3. BMC Neurol. 2024. PMID: 38263061 Free PMC article.
Rates of cortical thinning in Alzheimer's disease signature regions associate with vascular burden but not with β-amyloid status in cognitively normal adults at age 70.
Keuss SE, Coath W, Cash DM, Barnes J, Nicholas JM, Lane CA, Parker TD, Keshavan A, Buchanan SM, Wagen AZ, Storey M, Harris M, Lu K, James SN, Street R, Malone IB, Sudre CH, Thomas DL, Dickson JC, Barkhof F, Murray-Smith H, Wong A, Richards M, Fox NC, Schott JM. Keuss SE, et al. Among authors: james sn. J Neurol Neurosurg Psychiatry. 2024 Jan 10:jnnp-2023-332067. doi: 10.1136/jnnp-2023-332067. Online ahead of print. J Neurol Neurosurg Psychiatry. 2024. PMID: 38199813 Free article.
Neuroimaging, clinical and life course correlates of normal-appearing white matter integrity in 70-year-olds.
James SN, Manning EN, Storey M, Nicholas JM, Coath W, Keuss SE, Cash DM, Lane CA, Parker T, Keshavan A, Buchanan SM, Wagen A, Harris M, Malone I, Lu K, Needham LP, Street R, Thomas D, Dickson J, Murray-Smith H, Wong A, Freiberger T, Crutch SJ, Fox NC, Richards M, Barkhof F, Sudre CH, Barnes J, Schott JM. James SN, et al. Brain Commun. 2023 Aug 18;5(5):fcad225. doi: 10.1093/braincomms/fcad225. eCollection 2023. Brain Commun. 2023. PMID: 37680671 Free PMC article.
55 results