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Inflammatory and immune markers in HIV-infected older adults on long-term antiretroviral therapy: Persistent elevation of sCD14 and of proinflammatory effector memory T cells.
Watanabe M, Jergovic M, Davidson L, LaFleur BJ, Castaneda Y, Martinez C, Smithey MJ, Stowe RP, Haddad EK, Nikolich-Žugich J. Watanabe M, et al. Among authors: haddad ek. Aging Cell. 2022 Sep;21(9):e13681. doi: 10.1111/acel.13681. Epub 2022 Aug 16. Aging Cell. 2022. PMID: 35975357 Free PMC article.
Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors.
Metcalf TU, Cubas RA, Ghneim K, Cartwright MJ, Grevenynghe JV, Richner JM, Olagnier DP, Wilkinson PA, Cameron MJ, Park BS, Hiscott JB, Diamond MS, Wertheimer AM, Nikolich-Zugich J, Haddad EK. Metcalf TU, et al. Among authors: haddad ek. Aging Cell. 2015 Jun;14(3):421-32. doi: 10.1111/acel.12320. Epub 2015 Feb 27. Aging Cell. 2015. PMID: 25728020 Free PMC article.
Aging alters antiviral signaling pathways resulting in functional impairment in innate immunity in response to pattern recognition receptor agonists.
Connors J, Taramangalam B, Cusimano G, Bell MR, Matt SM, Runner K, Gaskill PJ, DeFilippis V, Nikolich-Žugich J, Kutzler MA, Haddad EK. Connors J, et al. Among authors: haddad ek. Geroscience. 2022 Oct;44(5):2555-2572. doi: 10.1007/s11357-022-00612-5. Epub 2022 Jul 18. Geroscience. 2022. PMID: 35849213 Free PMC article.
Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L; RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups. Takata H, et al. Among authors: haddad ek. EBioMedicine. 2022 Oct;84:104253. doi: 10.1016/j.ebiom.2022.104253. Epub 2022 Sep 8. EBioMedicine. 2022. PMID: 36088683 Free PMC article.
Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
Muir R, Metcalf T, Tardif V, Takata H, Phanuphak N, Kroon E, Colby DJ, Trichavaroj R, Valcour V, Robb ML, Michael NL, Ananworanich J, Trautmann L, Haddad EK; RV254/SEARCH010 RV304/SEARCH 013 Study Groups. Muir R, et al. Among authors: haddad ek. PLoS Pathog. 2016 Jul 27;12(7):e1005777. doi: 10.1371/journal.ppat.1005777. eCollection 2016 Jul. PLoS Pathog. 2016. PMID: 27463374 Free PMC article.
Delayed differentiation of potent effector CD8+ T cells reducing viremia and reservoir seeding in acute HIV infection.
Takata H, Buranapraditkun S, Kessing C, Fletcher JL, Muir R, Tardif V, Cartwright P, Vandergeeten C, Bakeman W, Nichols CN, Pinyakorn S, Hansasuta P, Kroon E, Chalermchai T, O'Connell R, Kim J, Phanuphak N, Robb ML, Michael NL, Chomont N, Haddad EK, Ananworanich J, Trautmann L; RV254/SEARCH010 and the RV304/SEARCH013 Study Groups. Takata H, et al. Among authors: haddad ek. Sci Transl Med. 2017 Feb 15;9(377):eaag1809. doi: 10.1126/scitranslmed.aag1809. Sci Transl Med. 2017. PMID: 28202771 Free PMC article.
Aging alters immune responses to vaccines.
Connors J, Haddad EK, Petrovas C. Connors J, et al. Among authors: haddad ek. Aging (Albany NY). 2021 Jan 28;13(2):1568-1570. doi: 10.18632/aging.202598. Epub 2021 Jan 28. Aging (Albany NY). 2021. PMID: 33510048 Free PMC article. No abstract available.
123 results