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Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike.
Cantoni D, Murray MJ, Kalemera MD, Dicken SJ, Stejskal L, Brown G, Lytras S, Coey JD, McKenna J, Bridgett S, Simpson D, Fairley D, Thorne LG, Reuschl AK, Forrest C, Ganeshalingham M, Muir L, Palor M, Jarvis L, Willett B, Power UF, McCoy LE, Jolly C, Towers GJ, Doores KJ, Robertson DL, Shepherd AJ, Reeves MB, Bamford CGG, Grove J. Cantoni D, et al. Among authors: shepherd aj. EMBO Rep. 2022 Oct 6;23(10):e54322. doi: 10.15252/embr.202154322. Epub 2022 Sep 1. EMBO Rep. 2022. PMID: 35999696 Free PMC article.
Cholesterol sensing by CD81 is important for hepatitis C virus entry.
Palor M, Stejskal L, Mandal P, Lenman A, Alberione MP, Kirui J, Moeller R, Ebner S, Meissner F, Gerold G, Shepherd AJ, Grove J. Palor M, et al. Among authors: shepherd aj. J Biol Chem. 2020 Dec 11;295(50):16931-16948. doi: 10.1074/jbc.RA120.014761. Epub 2020 Sep 8. J Biol Chem. 2020. PMID: 32900848 Free PMC article.
An entropic safety catch controls hepatitis C virus entry and antibody resistance.
Stejskal L, Kalemera MD, Lewis CB, Palor M, Walker L, Daviter T, Lees WD, Moss DS, Kremyda-Vlachou M, Kozlakidis Z, Gallo G, Bailey D, Rosenberg W, Illingworth CJR, Shepherd AJ, Grove J. Stejskal L, et al. Among authors: shepherd aj. Elife. 2022 Jul 7;11:e71854. doi: 10.7554/eLife.71854. Elife. 2022. PMID: 35796426 Free PMC article.
A computational Grid framework for immunological applications.
Halling-Brown MD, Moss DS, Sansom CE, Shepherd AJ. Halling-Brown MD, et al. Among authors: shepherd aj. Philos Trans A Math Phys Eng Sci. 2009 Jul 13;367(1898):2705-16. doi: 10.1098/rsta.2009.0046. Philos Trans A Math Phys Eng Sci. 2009. PMID: 19487206
ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale.
Halling-Brown M, Pappalardo F, Rapin N, Zhang P, Alemani D, Emerson A, Castiglione F, Duroux P, Pennisi M, Miotto O, Churchill D, Rossi E, Moss DS, Sansom CE, Bernaschi M, Lefranc MP, Brunak S, Lund O, Motta S, Lollini PL, Murgo A, Palladini A, Basford KE, Brusic V, Shepherd AJ. Halling-Brown M, et al. Among authors: shepherd aj. Philos Trans A Math Phys Eng Sci. 2010 Jun 13;368(1920):2799-815. doi: 10.1098/rsta.2010.0067. Philos Trans A Math Phys Eng Sci. 2010. PMID: 20439274
218 results