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Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike.
Cantoni D, Murray MJ, Kalemera MD, Dicken SJ, Stejskal L, Brown G, Lytras S, Coey JD, McKenna J, Bridgett S, Simpson D, Fairley D, Thorne LG, Reuschl AK, Forrest C, Ganeshalingham M, Muir L, Palor M, Jarvis L, Willett B, Power UF, McCoy LE, Jolly C, Towers GJ, Doores KJ, Robertson DL, Shepherd AJ, Reeves MB, Bamford CGG, Grove J. Cantoni D, et al. Among authors: willett b. EMBO Rep. 2022 Oct 6;23(10):e54322. doi: 10.15252/embr.202154322. Epub 2022 Sep 1. EMBO Rep. 2022. PMID: 35999696 Free PMC article.
Send cat and dog samples to test for SARS-CoV-2.
Murcia P, Streiker D, Philipe ADS, Robertson D, Jarrett R, Willett B, Hosie M, Biek R, Allan K, Weir W. Murcia P, et al. Among authors: willett b. Vet Rec. 2020 May 30;186(17):571. doi: 10.1136/vr.m2019. Epub 2020 May 25. Vet Rec. 2020. PMID: 32451348 No abstract available.
Detection of SARS-CoV-2 in respiratory samples from cats in the UK associated with human-to-cat transmission.
Hosie MJ, Epifano I, Herder V, Orton RJ, Stevenson A, Johnson N, MacDonald E, Dunbar D, McDonald M, Howie F, Tennant B, Herrity D, Da Silva Filipe A, Streicker DG; COVID-19 Genomics UK (COG-UK) consortium; Willett BJ, Murcia PR, Jarrett RF, Robertson DL, Weir W. Hosie MJ, et al. Among authors: willett bj. Vet Rec. 2021 Apr;188(8):e247. doi: 10.1002/vetr.247. Epub 2021 Apr 22. Vet Rec. 2021. PMID: 33890314 Free PMC article.
In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2.
Szemiel AM, Merits A, Orton RJ, MacLean OA, Pinto RM, Wickenhagen A, Lieber G, Turnbull ML, Wang S, Furnon W, Suarez NM, Mair D, da Silva Filipe A, Willett BJ, Wilson SJ, Patel AH, Thomson EC, Palmarini M, Kohl A, Stewart ME. Szemiel AM, et al. PLoS Pathog. 2021 Sep 17;17(9):e1009929. doi: 10.1371/journal.ppat.1009929. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34534263 Free PMC article.
Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection.
Dowell AC, Butler MS, Jinks E, Tut G, Lancaster T, Sylla P, Begum J, Bruton R, Pearce H, Verma K, Logan N, Tyson G, Spalkova E, Margielewska-Davies S, Taylor GS, Syrimi E, Baawuah F, Beckmann J, Okike IO, Ahmad S, Garstang J, Brent AJ, Brent B, Ireland G, Aiano F, Amin-Chowdhury Z, Jones S, Borrow R, Linley E, Wright J, Azad R, Waiblinger D, Davis C, Thomson EC, Palmarini M, Willett BJ, Barclay WS, Poh J, Amirthalingam G, Brown KE, Ramsay ME, Zuo J, Moss P, Ladhani S. Dowell AC, et al. Among authors: willett bj. Nat Immunol. 2022 Jan;23(1):40-49. doi: 10.1038/s41590-021-01089-8. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937928 Free PMC article.
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Willett BJ, Grove J, MacLean OA, Wilkie C, De Lorenzo G, Furnon W, Cantoni D, Scott S, Logan N, Ashraf S, Manali M, Szemiel A, Cowton V, Vink E, Harvey WT, Davis C, Asamaphan P, Smollett K, Tong L, Orton R, Hughes J, Holland P, Silva V, Pascall DJ, Puxty K, da Silva Filipe A, Yebra G, Shaaban S, Holden MTG, Pinto RM, Gunson R, Templeton K, Murcia PR, Patel AH, Klenerman P, Dunachie S; PITCH Consortium; COVID-19 Genomics UK (COG-UK) Consortium; Haughney J, Robertson DL, Palmarini M, Ray S, Thomson EC. Willett BJ, et al. Nat Microbiol. 2022 Aug;7(8):1161-1179. doi: 10.1038/s41564-022-01143-7. Epub 2022 Jul 7. Nat Microbiol. 2022. PMID: 35798890 Free PMC article.
Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Willett BJ, Grove J, MacLean OA, Wilkie C, De Lorenzo G, Furnon W, Cantoni D, Scott S, Logan N, Ashraf S, Manali M, Szemiel A, Cowton V, Vink E, Harvey WT, Davis C, Asamaphan P, Smollett K, Tong L, Orton R, Hughes J, Holland P, Silva V, Pascall DJ, Puxty K, da Silva Filipe A, Yebra G, Shaaban S, Holden MTG, Pinto RM, Gunson R, Templeton K, Murcia PR, Patel AH, Klenerman P, Dunachie S; PITCH Consortium; COVID-19 Genomics UK (COG-UK) Consortium; Haughney J, Robertson DL, Palmarini M, Ray S, Thomson EC. Willett BJ, et al. Nat Microbiol. 2022 Oct;7(10):1709. doi: 10.1038/s41564-022-01241-6. Nat Microbiol. 2022. PMID: 36114232 Free PMC article. No abstract available.
SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies.
Cox M, Peacock TP, Harvey WT, Hughes J, Wright DW; COVID-19 Genomics UK (COG-UK) Consortium; Willett BJ, Thomson E, Gupta RK, Peacock SJ, Robertson DL, Carabelli AM. Cox M, et al. Nat Rev Microbiol. 2023 Feb;21(2):112-124. doi: 10.1038/s41579-022-00809-7. Epub 2022 Oct 28. Nat Rev Microbiol. 2023. PMID: 36307535 Free PMC article. Review.
Immunological imprinting of humoral immunity to SARS-CoV-2 in children.
Dowell AC, Lancaster T, Bruton R, Ireland G, Bentley C, Sylla P, Zuo J, Scott S, Jadir A, Begum J, Roberts T, Stephens C, Ditta S, Shepherdson R, Powell AA, Brent AJ, Brent B, Baawuah F, Okike I, Beckmann J, Ahmad S, Aiano F, Garstang J, Ramsay ME, Azad R, Waiblinger D, Willett B, Wright J, Ladhani SN, Moss P. Dowell AC, et al. Among authors: willett b. Nat Commun. 2023 Jun 29;14(1):3845. doi: 10.1038/s41467-023-39575-2. Nat Commun. 2023. PMID: 37386081 Free PMC article.
159 results