de Laat B - Search Results

1

Absence of hyperfibrinolysis may explain lack of efficacy of tranexamic acid in hypoproliferative thrombocytopenia.

Ilich A, Gernsheimer TB, Triulzi DJ, Herren H, Brown SP, Holle LA, Lucas AT, de Laat B, El Kassar N, Wolberg AS, May S, Key NS. Ilich A, et al. Among authors: de laat b. Blood Adv. 2023 Mar 28;7(6):900-908. doi: 10.1182/bloodadvances.2022008255. Blood Adv. 2023. PMID: 36044391 Free PMC article.

2

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice.

Miszta A, Kopec AK, Pant A, Holle LA, Byrnes JR, Lawrence DA, Hansen KC, Flick MJ, Luyendyk JP, de Laat B, Wolberg AS. Miszta A, et al. Among authors: de laat b. Blood. 2020 May 7;135(19):1704-1717. doi: 10.1182/blood.2019004267. Blood. 2020. PMID: 32315384 Free PMC article.

3

Application of a plasmin generation assay to define pharmacodynamic effects of tranexamic acid in women undergoing cesarean delivery.

Miszta A, Ahmadzia HK, Luban NLC, Li S, Guo D, Holle LA, Berger JS, James AH, Gobburu JVS, van den Anker J, de Laat B, Wolberg AS. Miszta A, et al. Among authors: de laat b. J Thromb Haemost. 2021 Jan;19(1):221-232. doi: 10.1111/jth.15114. Epub 2020 Dec 26. J Thromb Haemost. 2021. PMID: 33001565 Free PMC article.

4

COVID-19 and Sepsis Are Associated With Different Abnormalities in Plasma Procoagulant and Fibrinolytic Activity.

Bouck EG, Denorme F, Holle LA, Middelton EA, Blair AM, de Laat B, Schiffman JD, Yost CC, Rondina MT, Wolberg AS, Campbell RA. Bouck EG, et al. Among authors: de laat b. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):401-414. doi: 10.1161/ATVBAHA.120.315338. Epub 2020 Nov 16. Arterioscler Thromb Vasc Biol. 2021. PMID: 33196292 Free PMC article.

5

Assessing Plasmin Generation in Health and Disease.

Miszta A, Huskens D, Donkervoort D, Roberts MJM, Wolberg AS, de Laat B. Miszta A, et al. Among authors: de laat b. Int J Mol Sci. 2021 Mar 9;22(5):2758. doi: 10.3390/ijms22052758. Int J Mol Sci. 2021. PMID: 33803235 Free PMC article. Review.

6

Plasma-based assays distinguish hyperfibrinolysis and shutdown subgroups in trauma-induced coagulopathy.

Lawson MA, Holle LA, Dow NE, Hennig G, de Laat B, Moore HB, Moore EE, Cohen MJ, Bouchard BA, Freeman K, Wolberg AS. Lawson MA, et al. Among authors: de laat b. J Trauma Acute Care Surg. 2022 Nov 1;93(5):579-587. doi: 10.1097/TA.0000000000003723. Epub 2022 Jun 10. J Trauma Acute Care Surg. 2022. PMID: 35687811 Free PMC article.

7

Crucial roles of red blood cells and platelets in whole blood thrombin generation.

Sun S, Campello E, Zou J, Konings J, Huskens D, Wan J, Fernández DI, Reutelingsperger CPM, Ten Cate H, Toffanin S, Bulato C, de Groot PG, de Laat B, Simioni P, Heemskerk JWM, Roest M. Sun S, et al. Among authors: de laat b, de groot pg. Blood Adv. 2023 Nov 14;7(21):6717-6731. doi: 10.1182/bloodadvances.2023010027. Blood Adv. 2023. PMID: 37648671 Free PMC article.

8

Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A.

Strilchuk AW, Hur WS, Batty P, Sang Y, Abrahams SR, Yong ASM, Leung J, Silva LM, Schroeder JA, Nesbitt K, de Laat B, Moutsopoulos NM, Bugge TH, Shi Q, Cullis PR, Merricks EP, Wolberg AS, Flick MJ, Lillicrap D, Nichols TC, Kastrup CJ. Strilchuk AW, et al. Among authors: de laat b. Sci Transl Med. 2024 Feb 21;16(735):eadh0027. doi: 10.1126/scitranslmed.adh0027. Epub 2024 Feb 21. Sci Transl Med. 2024. PMID: 38381848

9

Prothrombin conversion is accelerated in the antiphospholipid syndrome and insensitive to thrombomodulin.

Kremers RMW, Zuily S, Kelchtermans H, Peters TC, Bloemen S, Regnault V, Hemker HC, de Groot PG, Wahl D, de Laat B. Kremers RMW, et al. Among authors: de laat b, de groot pg. Blood Adv. 2018 Jun 12;2(11):1315-1324. doi: 10.1182/bloodadvances.2018018036. Blood Adv. 2018. PMID: 29895622 Free PMC article.

10

A thrombin-driven neural net diagnoses the antiphospholipid syndrome without the need for interruption of anticoagulation.

de Laat-Kremers RMW, Wahl D, Zuily S, Ninivaggi M, Regnault V, Musial J, de Groot PG, Devreese KMJ, de Laat B. de Laat-Kremers RMW, et al. Among authors: de laat b. Blood Adv. 2024 Feb 27;8(4):936-946. doi: 10.1182/bloodadvances.2023011938. Blood Adv. 2024. PMID: 38163323 Free PMC article.

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