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JAG1-NOTCH4 mechanosensing drives atherosclerosis.
Souilhol C, Tardajos Ayllon B, Li X, Diagbouga MR, Zhou Z, Canham L, Roddie H, Pirri D, Chambers EV, Dunning MJ, Ariaans M, Li J, Fang Y, Jørgensen HF, Simons M, Krams R, Waltenberger J, Fragiadaki M, Ridger V, De Val S, Francis SE, Chico TJ, Serbanovic-Canic J, Evans PC. Souilhol C, et al. Among authors: de val s. Sci Adv. 2022 Sep 2;8(35):eabo7958. doi: 10.1126/sciadv.abo7958. Epub 2022 Aug 31. Sci Adv. 2022. PMID: 36044575 Free PMC article.
SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M. Chiang IK, et al. Among authors: de val s. Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15. Development. 2017. PMID: 28619820 Free PMC article.
Venous identity requires BMP signalling through ALK3.
Neal A, Nornes S, Payne S, Wallace MD, Fritzsche M, Louphrasitthiphol P, Wilkinson RN, Chouliaras KM, Liu K, Plant K, Sholapurkar R, Ratnayaka I, Herzog W, Bond G, Chico T, Bou-Gharios G, De Val S. Neal A, et al. Among authors: de val s. Nat Commun. 2019 Jan 28;10(1):453. doi: 10.1038/s41467-019-08315-w. Nat Commun. 2019. PMID: 30692543 Free PMC article.
MEF2 transcription factors are key regulators of sprouting angiogenesis.
Sacilotto N, Chouliaras KM, Nikitenko LL, Lu YW, Fritzsche M, Wallace MD, Nornes S, García-Moreno F, Payne S, Bridges E, Liu K, Biggs D, Ratnayaka I, Herbert SP, Molnár Z, Harris AL, Davies B, Bond GL, Bou-Gharios G, Schwarz JJ, De Val S. Sacilotto N, et al. Among authors: de val s. Genes Dev. 2016 Oct 15;30(20):2297-2309. doi: 10.1101/gad.290619.116. Genes Dev. 2016. PMID: 27898394 Free PMC article.
Endothelial-Specific Cre Mouse Models.
Payne S, De Val S, Neal A. Payne S, et al. Among authors: de val s. Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2550-2561. doi: 10.1161/ATVBAHA.118.309669. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354251 Free PMC article. Review.
42 results