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JAG1-NOTCH4 mechanosensing drives atherosclerosis.
Souilhol C, Tardajos Ayllon B, Li X, Diagbouga MR, Zhou Z, Canham L, Roddie H, Pirri D, Chambers EV, Dunning MJ, Ariaans M, Li J, Fang Y, Jørgensen HF, Simons M, Krams R, Waltenberger J, Fragiadaki M, Ridger V, De Val S, Francis SE, Chico TJ, Serbanovic-Canic J, Evans PC. Souilhol C, et al. Among authors: fragiadaki m. Sci Adv. 2022 Sep 2;8(35):eabo7958. doi: 10.1126/sciadv.abo7958. Epub 2022 Aug 31. Sci Adv. 2022. PMID: 36044575 Free PMC article.
Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites.
Feng S, Bowden N, Fragiadaki M, Souilhol C, Hsiao S, Mahmoud M, Allen S, Pirri D, Ayllon BT, Akhtar S, Thompson AAR, Jo H, Weber C, Ridger V, Schober A, Evans PC. Feng S, et al. Among authors: fragiadaki m. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2087-2101. doi: 10.1161/ATVBAHA.117.309249. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882872 Free PMC article.
β1 integrin is a sensor of blood flow direction.
Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L, Akhtar N, Feng S, Ridger V, Waltho J, Pinteaux E, Humphries MJ, Bryan MT, Evans PC. Xanthis I, et al. Among authors: fragiadaki m. J Cell Sci. 2019 Jun 3;132(11):jcs229542. doi: 10.1242/jcs.229542. J Cell Sci. 2019. PMID: 31076511 Free PMC article.
Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science.
Evans PC, Rainger GE, Mason JC, Guzik TJ, Osto E, Stamataki Z, Neil D, Hoefer IE, Fragiadaki M, Waltenberger J, Weber C, Bochaton-Piallat ML, Bäck M. Evans PC, et al. Among authors: fragiadaki m. Cardiovasc Res. 2020 Dec 1;116(14):2177-2184. doi: 10.1093/cvr/cvaa230. Cardiovasc Res. 2020. PMID: 32750108 Free PMC article. Review.
29 results