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A microbial supply chain for production of the anti-cancer drug vinblastine.
Zhang J, Hansen LG, Gudich O, Viehrig K, Lassen LMM, Schrübbers L, Adhikari KB, Rubaszka P, Carrasquer-Alvarez E, Chen L, D'Ambrosio V, Lehka B, Haidar AK, Nallapareddy S, Giannakou K, Laloux M, Arsovska D, Jørgensen MAK, Chan LJG, Kristensen M, Christensen HB, Sudarsan S, Stander EA, Baidoo E, Petzold CJ, Wulff T, O'Connor SE, Courdavault V, Jensen MK, Keasling JD. Zhang J, et al. Among authors: courdavault v. Nature. 2022 Sep;609(7926):341-347. doi: 10.1038/s41586-022-05157-3. Epub 2022 Aug 31. Nature. 2022. PMID: 36045295 Free PMC article.
Gaining access to acetyl-CoA by peroxisomal surface display.
Perrot T, Besseau S, Papon N, Courdavault V. Perrot T, et al. Among authors: courdavault v. Synth Syst Biotechnol. 2023 Mar 6;8(2):224-226. doi: 10.1016/j.synbio.2023.02.003. eCollection 2023 Jun. Synth Syst Biotechnol. 2023. PMID: 36936387 Free PMC article.
A pair of tabersonine 16-hydroxylases initiates the synthesis of vindoline in an organ-dependent manner in Catharanthus roseus.
Besseau S, Kellner F, Lanoue A, Thamm AM, Salim V, Schneider B, Geu-Flores F, Höfer R, Guirimand G, Guihur A, Oudin A, Glevarec G, Foureau E, Papon N, Clastre M, Giglioli-Guivarc'h N, St-Pierre B, Werck-Reichhart D, Burlat V, De Luca V, O'Connor SE, Courdavault V. Besseau S, et al. Among authors: courdavault v. Plant Physiol. 2013 Dec;163(4):1792-803. doi: 10.1104/pp.113.222828. Epub 2013 Oct 9. Plant Physiol. 2013. PMID: 24108213 Free PMC article.
De novo production of the plant-derived alkaloid strictosidine in yeast.
Brown S, Clastre M, Courdavault V, O'Connor SE. Brown S, et al. Among authors: courdavault v. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3205-10. doi: 10.1073/pnas.1423555112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675512 Free PMC article.
158 results