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Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
García-Alonso S, Mesa P, Ovejero LP, Aizpurua G, Lechuga CG, Zarzuela E, Santiveri CM, Sanclemente M, Muñoz J, Musteanu M, Campos-Olivas R, Martínez-Torrecuadrada J, Barbacid M, Montoya G. García-Alonso S, et al. Mol Cell. 2022 Sep 15;82(18):3438-3452.e8. doi: 10.1016/j.molcel.2022.08.012. Epub 2022 Sep 1. Mol Cell. 2022. PMID: 36055235 Free article.
RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression.
Sanclemente M, Nieto P, Garcia-Alonso S, Fernández-García F, Esteban-Burgos L, Guerra C, Drosten M, Caleiras E, Martinez-Torrecuadrada J, Santamaría D, Musteanu M, Barbacid M. Sanclemente M, et al. Cancer Cell. 2021 Mar 8;39(3):294-296. doi: 10.1016/j.ccell.2021.01.008. Epub 2021 Jan 28. Cancer Cell. 2021. PMID: 33513349 Free article. No abstract available.
Multisite phosphorylation of P-Rex1 by protein kinase C.
Montero JC, Seoane S, García-Alonso S, Pandiella A. Montero JC, et al. Oncotarget. 2016 Nov 22;7(47):77937-77949. doi: 10.18632/oncotarget.12846. Oncotarget. 2016. PMID: 27788493 Free PMC article.
mTOR Inhibition and T-DM1 in HER2-Positive Breast Cancer.
Casadevall D, Hernández-Prat A, García-Alonso S, Arpí-Llucià O, Menéndez S, Qin M, Guardia C, Morancho B, Sánchez-Martín FJ, Zazo S, Gavilán E, Sabbaghi MA, Eroles P, Cejalvo JM, Lluch A, Rojo F, Pandiella A, Rovira A, Albanell J. Casadevall D, et al. Among authors: garcia alonso s. Mol Cancer Res. 2022 Jul 6;20(7):1108-1121. doi: 10.1158/1541-7786.MCR-21-0545. Mol Cancer Res. 2022. PMID: 35348729
Resistance to Antibody-Drug Conjugates.
García-Alonso S, Ocaña A, Pandiella A. García-Alonso S, et al. Cancer Res. 2018 May 1;78(9):2159-2165. doi: 10.1158/0008-5472.CAN-17-3671. Epub 2018 Apr 13. Cancer Res. 2018. PMID: 29653942 Review.
The WNK1-ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib.
Sánchez-Fdez A, Matilla-Almazán S, Montero JC, Del Carmen S, Abad M, García-Alonso S, Bhattacharya S, Calar K, de la Puente P, Ocaña A, Pandiella A, Esparís-Ogando A. Sánchez-Fdez A, et al. Among authors: garcia alonso s. Clin Transl Med. 2023 Apr;13(4):e1217. doi: 10.1002/ctm2.1217. Clin Transl Med. 2023. PMID: 37029785 Free PMC article.
34 results