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Leveraging big data of immune checkpoint blockade response identifies novel potential targets.
Bareche Y, Kelly D, Abbas-Aghababazadeh F, Nakano M, Esfahani PN, Tkachuk D, Mohammad H, Samstein R, Lee CH, Morris LGT, Bedard PL, Haibe-Kains B, Stagg J. Bareche Y, et al. Among authors: bedard pl. Ann Oncol. 2022 Dec;33(12):1304-1317. doi: 10.1016/j.annonc.2022.08.084. Epub 2022 Aug 30. Ann Oncol. 2022. PMID: 36055464 Free article. Review.
A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).
Mateo J, Chakravarty D, Dienstmann R, Jezdic S, Gonzalez-Perez A, Lopez-Bigas N, Ng CKY, Bedard PL, Tortora G, Douillard JY, Van Allen EM, Schultz N, Swanton C, André F, Pusztai L. Mateo J, et al. Among authors: bedard pl. Ann Oncol. 2018 Sep 1;29(9):1895-1902. doi: 10.1093/annonc/mdy263. Ann Oncol. 2018. PMID: 30137196 Free PMC article.
Genomic alterations in breast cancer: level of evidence for actionability according to ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).
Condorelli R, Mosele F, Verret B, Bachelot T, Bedard PL, Cortes J, Hyman DM, Juric D, Krop I, Bieche I, Saura C, Sotiriou C, Cardoso F, Loibl S, Andre F, Turner NC. Condorelli R, et al. Among authors: bedard pl. Ann Oncol. 2019 Mar 1;30(3):365-373. doi: 10.1093/annonc/mdz036. Ann Oncol. 2019. PMID: 30715161 Free article.
Ocular toxicities of MEK inhibitors and other targeted therapies.
Stjepanovic N, Velazquez-Martin JP, Bedard PL. Stjepanovic N, et al. Among authors: bedard pl. Ann Oncol. 2016 Jun;27(6):998-1005. doi: 10.1093/annonc/mdw100. Epub 2016 Mar 6. Ann Oncol. 2016. PMID: 26951625 Free article. Review.
Safety, pharmacokinetics, and antitumor activity of the anti-CEACAM5-DM4 antibody-drug conjugate tusamitamab ravtansine (SAR408701) in patients with advanced solid tumors: first-in-human dose-escalation study.
Gazzah A, Bedard PL, Hierro C, Kang YK, Abdul Razak A, Ryu MH, Demers B, Fagniez N, Henry C, Hospitel M, Soria JC, Tabernero J. Gazzah A, et al. Among authors: bedard pl. Ann Oncol. 2022 Apr;33(4):416-425. doi: 10.1016/j.annonc.2021.12.012. Epub 2022 Jan 10. Ann Oncol. 2022. PMID: 35026412 Free article. Clinical Trial.
Delayed immune-related adverse events in assessment for dose-limiting toxicity in early phase immunotherapy trials.
Kanjanapan Y, Day D, Butler MO, Wang L, Joshua AM, Hogg D, Leighl NB, Razak ARA, Hansen AR, Boujos S, Chappell M, Chow K, Sherwin B, Stayner LA, Soultani L, Zambrana A, Siu LL, Bedard PL, Spreafico A. Kanjanapan Y, et al. Among authors: bedard pl. Eur J Cancer. 2019 Jan;107:1-7. doi: 10.1016/j.ejca.2018.10.017. Epub 2018 Dec 7. Eur J Cancer. 2019. PMID: 30529898
221 results